Head-to-head · WeighScore
Medi-Weightloss vs Signos
The verdict
Medi-Weightloss takes it — 69.6/100 to 61.4/100.
Medi-Weightloss grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Medi-Weightloss is an established physician-supervised weight-loss brand with 130-plus locations nationwide plus telehealth.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Medi-Weightloss | Signos |
|---|---|---|
| WeighScore | 69.6/100 | 61.4/100 |
| Grade | C | C |
| Scorecard rank | #126 | #294 |
| Semaglutide | $199/mo (promotional rate, brand-name) | $199/mo (6-month plan, compounded) |
| Tirzepatide | Not disclosed | $199/mo (starting dose, compounded) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #126 · C
Strengths
- Both branded (Wegovy, Zepbound) and compounded semaglutide/tirzepatide
- Established brand with 130+ physician-supervised locations nationwide
- Telehealth plus in-person clinic options
- Accepts insurance at many locations; HSA/FSA welcome
- Includes body-composition analysis and personalized plans
Where it loses points
- Ongoing medication pricing not transparently posted; varies by plan
- $199 new-patient visit fee before medication costs
- Frequent (often weekly) visits expected for some patients
- Compounded products are not FDA-approved or evaluated
Graded #294 · C
Strengths
- Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
- Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
- Free rapid shipping; HSA/FSA eligible
- Real-time glucose insights and app coaching to help sustain results after GLP-1
Where it loses points
- Compounded GLP-1s are not FDA-approved finished products
- Headline price is a 6-month-program rate, not month-to-month
- Only semaglutide is shown in the program; tirzepatide availability is not confirmed
- Compounding pharmacy partner and state availability are not published on the landing page
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.