Head-to-head · WeighScore
MadeMed vs Southern Vitality and Weight Loss
The verdict
MadeMed takes it — 80.4/100 to 74.2/100.
MadeMed grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Publishes its price at every single dose, so what a titrated dose costs is knowable on day one.
We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | MadeMed | Southern Vitality and Weight Loss |
|---|---|---|
| WeighScore | 80.4/100 | 74.2/100 |
| Grade | B− | C |
| Scorecard rank | #30 | #67 |
| Semaglutide | $239/mo quarterly (from $199/mo on 6 months) | $99/mo (starting dose, compounded) |
| Tirzepatide | $399/mo quarterly (from $369/mo on 6 months) | $99/mo (starting dose, compounded) |
| Coverage | 40 states | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Injection only |
Graded #30 · B−
Strengths
- One flat price at every dose, published dose by dose — semaglutide 0.25–2.4mg, tirzepatide 2.5–15mg
- LegitScript verified, with board-certified physician review and US compounding pharmacies
- Full refund minus a $39 visit fee if you are not prescribed, stated before checkout
- Oral semaglutide and oral tirzepatide alongside the injections; free overnight shipping with supplies
Where it loses points
- The most expensive tirzepatide here at $399/mo quarterly
- 40 states rather than nationwide
- No published recurring lab programme
- Ships one vial every two months, a less flexible cadence than a monthly refill
Graded #67 · C
Strengths
- Compounded GLP-1 (semaglutide and tirzepatide) starting as low as $99/mo
- Names its compounding pharmacy partners (PerfectRx, The Pharmacy Hub, RX Compound Store) — uncommon transparency
- Free telehealth consult and free shipping; no membership or hidden fees
- Bi-weekly check-ins; operating since 2012
- Flexible monthly financing available at checkout
Where it loses points
- All sales final once a prescription is approved and sent to the pharmacy
- States of operation not published
- Not LegitScript-certified (no certification displayed)
- Prescribing medical group not named (only "licensed providers")
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.