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Head-to-head · WeighScore

LillyDirect Foundayo vs Roen Rx

LillyDirect Foundayo
Graded #173

Higher grade

vs+8.200000000000003
Roen Rx
Graded #350

Lower grade

The verdict

LillyDirect Foundayo takes it — 67.2/100 to 59/100.

LillyDirect Foundayo grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Eli Lilly's manufacturer direct-pay channel for Foundayo (orforglipron), the first oral GLP-1 pill for weight loss.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueLillyDirect Foundayo +34
72
38
Dose & formulationRoen Rx +18
59
77
Clinical oversightLillyDirect Foundayo +4
78
74
Labs & monitoringRoen Rx +1
52
53
FulfillmentLillyDirect Foundayo +13
80
67
Contract termsLillyDirect Foundayo +14
55
41
LillyDirect Foundayo · left barRoen Rx · right bar

The numbers

MetricLillyDirect FoundayoRoen Rx
WeighScore67.2/10059/100
GradeCC
Scorecard rank#173#350
SemaglutideNot disclosed$151/mo (3-month plan, plus a separate fee, compounded)
TirzepatideNot disclosed$216/mo (plus a separate fee, compounded)
CoverageAll 50 statesCoverage not published
Brand-name accessYesYes
Oral / sublingualYesInjection only
LillyDirect Foundayo

Graded #173 · C

Strengths

  • Cheapest legal path to a brand-name GLP-1 in 2026 ($25/mo with savings card for commercial insurance)
  • Direct from manufacturer — no compounding, no third-party reseller
  • Daily oral pill, no injections, no refrigeration
  • Available in all 50 states

Where it loses points

  • Lower mean weight loss vs Wegovy (14.9%) and Zepbound (20.9%) — labeled-dose 11.1% per Foundayo PI
  • Requires existing prescription from a separate prescriber (LillyDirect does not write the prescription)
  • $25 savings card requires commercial insurance — Medicare and Medicaid not eligible
  • Strict empty-stomach 30-minute window may be hard for some patients to follow
Roen Rx

Graded #350 · C

Strengths

  • Insurance coordination for brand-name GLP-1s — as low as $25/mo
  • Both compounded and brand-name options
  • LegitScript approved with Compounded USA badge
  • Compounded semaglutide from $151/mo quarterly
  • Also offers primary care, mental health, and other specialties

Where it loses points

  • State availability not publicly disclosed
  • Insurance coordination may not work for all plans
  • Broader platform (ED, hair loss, skincare, birth control)
  • Requires a separate membership (first month $39); GLP-1 medications are NOT included in the membership fee - medication is billed on top

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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