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Head-to-head · WeighScore

LeanDose vs Signos

LeanDose
Graded #167

Higher grade

vs+5.699999999999996
Signos
Graded #293

Lower grade

The verdict

LeanDose takes it — 67.1/100 to 61.4/100.

LeanDose grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. LeanDose is a doctor-guided compounded GLP-1 telehealth service for eligible adults, with transparent all-inclusive first-month pricing: compounded semaglutide from $159 and tirzepatide from $279.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueLeanDose +22
66
44
Dose & formulationEven
64
64
Clinical oversightSignos +5
79
84
Labs & monitoringSignos +17
54
71
FulfillmentLeanDose +8
79
71
Contract termsLeanDose +35
55
20
LeanDose · left barSignos · right bar

The numbers

MetricLeanDoseSignos
WeighScore67.1/10061.4/100
GradeCC
Scorecard rank#167#293
Semaglutide$159/mo (first-month rate, compounded)$199/mo (6-month plan, compounded)
Tirzepatide$279/mo (first-month rate, compounded)$199/mo (starting dose, compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
LeanDose

Graded #167 · C

Strengths

  • Transparent all-inclusive first-month pricing (compounded semaglutide from $159, tirzepatide from $279)
  • Verifiable LegitScript certification (seal ID 49840868) and an FDA-registered compounding pharmacy
  • Doctor-prescribed and supervised, with personalized care plans and multi-state clinical support
  • Convenient at-home delivery; compounded semaglutide and tirzepatide options
  • Honest, modest social proof — 119 five-star patient reviews

Where it loses points

  • Compounded medications are not FDA-approved — not brand Wegovy, Ozempic, Zepbound, or Mounjaro
  • Headline rates are first-month pricing; your ongoing monthly cost may be higher
  • Available in multiple states but the full list is not published on the homepage
  • The compounding pharmacy is FDA-registered but not named
Signos

Graded #293 · C

Strengths

  • Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
  • Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
  • Free rapid shipping; HSA/FSA eligible
  • Real-time glucose insights and app coaching to help sustain results after GLP-1

Where it loses points

  • Compounded GLP-1s are not FDA-approved finished products
  • Headline price is a 6-month-program rate, not month-to-month
  • Only semaglutide is shown in the program; tirzepatide availability is not confirmed
  • Compounding pharmacy partner and state availability are not published on the landing page

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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