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Head-to-head · WeighScore

Knownwell vs Sesame Care

Knownwell
Graded #191

Lower grade

vs+20.9
Sesame Care
Graded #2

Higher grade

The verdict

Sesame Care takes it — 87.8/100 to 66.9/100.

Sesame Care grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. An established national telehealth marketplace with the widest real brand-name GLP-1 access in the ranking — Wegovy (pen and pill), Zepbound, Ozempic and Mounjaro — plus provider-by-provider price transparency.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueSesame Care +46
38
84
Dose & formulationSesame Care +16
76
92
Clinical oversightSesame Care +4
90
94
Labs & monitoringSesame Care +21
63
84
FulfillmentKnownwell +6
86
80
Contract termsSesame Care +37
55
92
Knownwell · left barSesame Care · right bar

The numbers

MetricKnownwellSesame Care
WeighScore66.9/10087.8/100
GradeCB+
Scorecard rank#191#2
SemaglutideNot disclosedBrand Wegovy pill from $149/mo at 1.5 and 4 mg only, $299/mo at 9 and 25 mg — plus Sesame care: $59/mo only on the 12-month prepay, otherwise $99 billed every 28 days (13 charges a year)
Tirzepatide$349/mo (brand Zepbound)Brand Zepbound vial $299/mo (2.5 mg), $399 (5 mg), $449 (7.5–15 mg); KwikPen $299 / $399 / $499 / $699 (10–15 mg) — plus Sesame care: $59/mo on the 12-month prepay, otherwise $99 per 28 days
CoverageAll 50 statesNationwide marketplace
Brand-name accessYesYes
Oral / sublingualYesYes
Knownwell

Graded #191 · C

Strengths

  • Co-founded by obesity-medicine specialist Dr. Angela Fitch
  • Branded FDA-approved GLP-1s (Wegovy, Zepbound, Ozempic, Saxenda)
  • Official LillyDirect provider and Novo Wegovy-pill telehealth partner
  • Accepts insurance, copays as low as $25 for covered patients
  • Weight-inclusive care with dietitians and health coaches

Where it loses points

  • Specific self-pay monthly medication prices not transparently posted
  • In-person clinics limited to four metro areas
  • Branded-only focus can mean higher cost than compounded routes
Sesame Care

Graded #2 · B+

Strengths

  • Real FDA-approved brand-name access — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and Rybelsus
  • Established platform (operating since 2018) with LegitScript, BBB accreditation and large third-party review volume
  • You choose the provider and see the price up front — genuine marketplace transparency
  • Oral routes available (Wegovy pill, Rybelsus)

Where it loses points

  • A generalist marketplace, not a dedicated weight-loss program — lighter ongoing hand-holding than a specialist desk
  • Two-part cost (a platform subscription plus the medication) makes the true monthly total harder to compare
  • Brand-name cash prices can run high without insurance

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 544 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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