Head-to-head · WeighScore
Joi + Blokes vs Signos
The verdict
Joi + Blokes takes it — 66.1/100 to 61.4/100.
Joi + Blokes grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Joi + Blokes is a hormone-first telehealth platform with parallel programs for women (Joi) and men (Blokes), now expanded to compounded GLP-1s for weight loss.
We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Joi + Blokes | Signos |
|---|---|---|
| WeighScore | 66.1/100 | 61.4/100 |
| Grade | C | C |
| Scorecard rank | #203 | #293 |
| Semaglutide | $199/mo (promotional rate, quarterly plan, compounded) | $199/mo (6-month plan, compounded) |
| Tirzepatide | $299/mo (quarterly plan, compounded) | $199/mo (starting dose, compounded) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #203 · C
Strengths
- Separate programs for women (Joi) and men (Blokes) — most GLP-1 telehealth is gender-agnostic
- Trustpilot 4.6/5 from 1,254+ reviews — among the strongest review signals in the category
- Monthly price includes medication, dosing support, clinician consults, and health coaching
- Integrated hormone + GLP-1 programs help patients on testosterone or perimenopausal protocols
- First-month discount ($99 sema / $149 tirz) lowers the barrier to trying GLP-1s
Where it loses points
- Billed quarterly — a 3-month commitment up front, not month-to-month
- Different pricing in NY and NJ — verify your state's cost before committing
- Per-state availability isn't listed; it's zip-code gated behind signup
- Months 2+ cost more ($199 sema / $299 tirz) than the headline intro price
- No FDA-approved Wegovy — compounded only on the GLP-1 side; Zepbound carries a separate visit fee
Graded #293 · C
Strengths
- Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
- Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
- Free rapid shipping; HSA/FSA eligible
- Real-time glucose insights and app coaching to help sustain results after GLP-1
Where it loses points
- Compounded GLP-1s are not FDA-approved finished products
- Headline price is a 6-month-program rate, not month-to-month
- Only semaglutide is shown in the program; tirzepatide availability is not confirmed
- Compounding pharmacy partner and state availability are not published on the landing page
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.