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Head-to-head · WeighScore

Immortals vs Southern Vitality and Weight Loss

Immortals
Graded #286

Lower grade

vs+12.400000000000006
Southern Vitality and Weight Loss
Graded #67

Higher grade

The verdict

Southern Vitality and Weight Loss takes it — 74.2/100 to 61.8/100.

Southern Vitality and Weight Loss grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Southern Vitality and Weight Loss is a physician-supervised telehealth weight-loss program (operating since 2012) offering compounded semaglutide and tirzepatide starting as low as $99/mo, plus vitamin…

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueSouthern Vitality and Weight Loss +30
54
84
Dose & formulationEven
64
64
Clinical oversightImmortals +1
88
87
Labs & monitoringSouthern Vitality and Weight Loss +10
54
64
FulfillmentSouthern Vitality and Weight Loss +3
68
71
Contract termsSouthern Vitality and Weight Loss +41
20
61
Immortals · left barSouthern Vitality and Weight Loss · right bar

The numbers

MetricImmortalsSouthern Vitality and Weight Loss
WeighScore61.8/10074.2/100
GradeCC
Scorecard rank#286#67
Semaglutide$167/mo (microdose tier, compounded)$99/mo (starting dose, compounded)
Tirzepatide$180/mo (microdose tier, compounded)$99/mo (starting dose, compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
Immortals

Graded #286 · C

Strengths

  • LegitScript certified (ID 50458743) with board-certified U.S. physician review within 72 hours
  • Physician consult + prescription bundled in price — 'You pay for treatment. That's it' with no added fees
  • Competitive pricing: semaglutide microdose from $167/month, tirzepatide from $180/month (promotional)
  • Unlimited provider messaging for 12 months included; video consults available
  • Founded by Bryan Johnson and Kate Tolo; clinical lead Dr. Carl Seger, M.D. (preventive/longevity medicine)

Where it loses points

  • Microdose framing uses sub-clinical doses — lower weight-loss efficacy than standard GLP-1 protocols
  • Quarterly commitment only — 3-month minimum, paid upfront ($501–$540/quarter); no monthly flexibility
  • State availability not publicly listed; 'eligible U.S. states' with no specific state list
  • Labs not included; baseline bloodwork protocol not disclosed on any public page
  • Compounding pharmacy not named; no 503A/503B accreditation details disclosed

Strengths

  • Compounded GLP-1 (semaglutide and tirzepatide) starting as low as $99/mo
  • Names its compounding pharmacy partners (PerfectRx, The Pharmacy Hub, RX Compound Store) — uncommon transparency
  • Free telehealth consult and free shipping; no membership or hidden fees
  • Bi-weekly check-ins; operating since 2012
  • Flexible monthly financing available at checkout

Where it loses points

  • All sales final once a prescription is approved and sent to the pharmacy
  • States of operation not published
  • Not LegitScript-certified (no certification displayed)
  • Prescribing medical group not named (only "licensed providers")

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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