Head-to-head · WeighScore
Harper Meds vs Signos
The verdict
Harper Meds takes it — 72.2/100 to 61.4/100.
Harper Meds grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. DTC telehealth weight-loss program (Nexus Health Solutions LLC) offering flat-rate compounded semaglutide and tirzepatide, with the consultation, prescription, medication, and shipping bundled into one…
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Harper Meds | Signos |
|---|---|---|
| WeighScore | 72.2/100 | 61.4/100 |
| Grade | C | C |
| Scorecard rank | #82 | #293 |
| Semaglutide | $149/mo | $199/mo (6-month plan, compounded) |
| Tirzepatide | $196/mo | $199/mo (starting dose, compounded) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #82 · C
Strengths
- Flat pricing — same cost at every dose, no escalation as you titrate up
- All-inclusive: doctor consultation, prescription, medication, and free shipping in one price
- LegitScript-certified; prescriptions reviewed by US-licensed M.D.s
- Offers both compounded semaglutide ($149/mo) and tirzepatide ($196/mo)
Where it loses points
- Membership fee is non-refundable once paid
- Partner pharmacy is not publicly named
- State availability not published (limited to 'certain states')
Graded #293 · C
Strengths
- Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
- Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
- Free rapid shipping; HSA/FSA eligible
- Real-time glucose insights and app coaching to help sustain results after GLP-1
Where it loses points
- Compounded GLP-1s are not FDA-approved finished products
- Headline price is a 6-month-program rate, not month-to-month
- Only semaglutide is shown in the program; tirzepatide availability is not confirmed
- Compounding pharmacy partner and state availability are not published on the landing page
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.