Head-to-head · WeighScore
Good Girl Rx vs Signos
The verdict
Good Girl Rx takes it — 62.1/100 to 61.4/100, but only just.
Good Girl Rx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Good Girl Rx (Good Girl LLC) offers compounded semaglutide and tirzepatide in injectable, microdose, and oral dissolving tablet (ODT) formats. Signos is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Good Girl Rx | Signos |
|---|---|---|
| WeighScore | 62.1/100 | 61.4/100 |
| Grade | C | C |
| Scorecard rank | #277 | #293 |
| Semaglutide | $79/mo (microdose tier, 12-month plan, compounded) | $199/mo (6-month plan, compounded) |
| Tirzepatide | $139/mo (microdose tier, 12-month plan, compounded) | $199/mo (starting dose, compounded) |
| Coverage | All 50 states | Coverage not published |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Yes | Injection only |
Graded #277 · C
Strengths
- LegitScript certified
- Multiple formats — injectable, microdose, and ODT pills — for both semaglutide and tirzepatide
- Dispensed by licensed 503A or 503B pharmacies
- Limited brand-name options available (Ozempic, Wegovy, Zepbound, Mounjaro)
- Named legal entity with a Nashville address
Where it loses points
- The advertised rates require twelve months paid up front; billed month to month the same products are $184 and $244, roughly 2.3 times as much
- Every plan is prepaid — the discount exists only on the 3-, 6- and 12-month terms
- The priced products are microdoses, not labelled therapeutic doses; the standard compounded semaglutide is $134/mo and also needs a year up front
- Compounded semaglutide and tirzepatide are not FDA-approved finished products
Graded #293 · C
Strengths
- Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
- Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
- Free rapid shipping; HSA/FSA eligible
- Real-time glucose insights and app coaching to help sustain results after GLP-1
Where it loses points
- Compounded GLP-1s are not FDA-approved finished products
- Headline price is a 6-month-program rate, not month-to-month
- Only semaglutide is shown in the program; tirzepatide availability is not confirmed
- Compounding pharmacy partner and state availability are not published on the landing page
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.