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Head-to-head · WeighScore

Fifty 410 vs Southern Vitality and Weight Loss

Fifty 410
Graded #94

Higher grade

vs+6.099999999999994
Southern Vitality and Weight Loss
Graded #227

Lower grade

The verdict

Fifty 410 takes it — 71.3/100 to 65.2/100.

Fifty 410 grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Fifty 410 is a direct-to-consumer weight-loss telehealth service offering personalized compounded semaglutide and tirzepatide prescribed by licensed providers and prepared by FDA-registered 503A and 503B…

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueFifty 410 +32
86
54
Dose & formulationFifty 410 +8
72
64
Clinical oversightSouthern Vitality and Weight Loss +7
80
87
Labs & monitoringSouthern Vitality and Weight Loss +1
53
54
FulfillmentEven
71
71
Contract termsSouthern Vitality and Weight Loss +24
37
61
Fifty 410 · left barSouthern Vitality and Weight Loss · right bar

The numbers

MetricFifty 410Southern Vitality and Weight Loss
WeighScore71.3/10065.2/100
GradeCC
Scorecard rank#94#227
Semaglutide$99/mo (all doses, compounded)$199/mo (compounded)
Tirzepatide$133/mo (starting dose, compounded)$299/mo (compounded)
CoverageCoverage not published1 state
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
Fifty 410

Graded #94 · C

Strengths

  • Transparent public pricing from 99 dollars per month for semaglutide
  • No membership or subscription; pay only for what you need
  • Compounded by FDA-registered 503A and 503B pharmacies
  • Fast 24 to 48 hour provider review
  • Free one to two day shipping

Where it loses points

  • Does not bill insurance directly
  • Compounded GLP-1 is not an FDA-approved finished drug
  • Specific clinician credentials are not publicly disclosed
  • Served-states list is not published on the site
  • No branded GLP-1 options

Strengths

  • Compounded GLP-1 (semaglutide and tirzepatide) starting as low as $99/mo
  • Names its compounding pharmacy partners (PerfectRx, The Pharmacy Hub, RX Compound Store) — uncommon transparency
  • Free telehealth consult and free shipping; no membership or hidden fees
  • Bi-weekly check-ins; operating since 2012
  • Flexible monthly financing available at checkout

Where it loses points

  • This is one physical clinic in Valdosta, Georgia, not a national telehealth service — nothing here is available to a reader outside Georgia
  • The advertised 'as low as $99/month' is a semaglutide three-month starter pack ($299 paid up front), not a tirzepatide rate and not a monthly one
  • Month-to-month rates are $199 semaglutide and $299 tirzepatide
  • Compounded semaglutide and tirzepatide are not FDA-approved finished products

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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