Head-to-head · WeighScore
Enhance MD vs Synergy Rx
The verdict
Enhance MD takes it — 84.8/100 to 76.2/100.
Enhance MD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. A transparently tiered compounded program — semaglutide $212/mo (first month $112), tirzepatide $280, a $169 microdose, and a $322 combo — backed by six-month lab testing and provider care, with NAD+ on the side.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Enhance MD | Synergy Rx |
|---|---|---|
| WeighScore | 84.8/100 | 76.2/100 |
| Grade | B | C |
| Scorecard rank | #11 | #41 |
| Semaglutide | $212/mo | From $199/mo |
| Tirzepatide | $280/mo | From $349/mo |
| Coverage | Not publicly listed | Not disclosed |
| Brand-name access | Compounded only | Yes |
| Oral / sublingual | Injection only | Injection only |
Graded #11 · B
Strengths
- Transparent tiered pricing across sema, tirz, microdose, and combo
- Dose-flat — the price does not step up as you titrate
- Six-month lab testing plus provider-led care
- NAD+ longevity adjacency available
Where it loses points
- Compounded only — no brand-name Ozempic/Wegovy or Mounjaro/Zepbound
- No oral or sublingual route
- States served are not published
- Higher entry price than the cheapest compounded programs
Graded #41 · C
Strengths
- Prescribes FDA-approved brand Wegovy, Ozempic and Mounjaro when clinically appropriate
- Unlimited appointments, unlimited messaging and 24/7 access to a dedicated clinical team
- $100 welcome credit at checkout, and FSA/HSA eligible
Where it loses points
- Publishes no GLP-1 price anywhere on its own site
- At $349/mo tirzepatide sits roughly $100 above the compounded median we track
- Does not publish which states it serves
- No published cancellation or refund terms
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.