Head-to-head · WeighScore
Enhance MD vs Rylo Health
The verdict
Enhance MD takes it — 84.8/100 to 64.7/100.
Enhance MD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. A transparently tiered compounded program — semaglutide $212/mo (first month $112), tirzepatide $280, a $169 microdose, and a $322 combo — backed by six-month lab testing and provider care, with NAD+ on the side.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Enhance MD | Rylo Health |
|---|---|---|
| WeighScore | 84.8/100 | 64.7/100 |
| Grade | B | C |
| Scorecard rank | #11 | #236 |
| Semaglutide | $212/mo | $149/mo (promotional rate, compounded) |
| Tirzepatide | $280/mo | $249/mo (compounded) |
| Coverage | Not publicly listed | All 50 states |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #11 · B
Strengths
- Transparent tiered pricing across sema, tirz, microdose, and combo
- Dose-flat — the price does not step up as you titrate
- Six-month lab testing plus provider-led care
- NAD+ longevity adjacency available
Where it loses points
- Compounded only — no brand-name Ozempic/Wegovy or Mounjaro/Zepbound
- No oral or sublingual route
- States served are not published
- Higher entry price than the cheapest compounded programs
Graded #236 · C
Strengths
- Names its dispensing pharmacy in full, with address and phone: VialsRX in Houston, Texas
- Names its medical group, Lone Star Virtual Health PLLC, and gives a provider contact
- Standard prices published openly alongside the promotional rate, so the real ongoing cost is visible
- Cancel in one click from the patient portal, with no contracts and no cancellation fees
- Peptide line priced openly, including NAD+ and sermorelin
Where it loses points
- Headline $100 and $160 rates are limited to the first 20 patients; standard rates are $149 and $249
- No LegitScript certification is claimed or displayed
- Several peptide products are advertised as coming soon rather than available
- No published refund policy beyond the no-cancellation-fee statement
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.