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Head-to-head · WeighScore

DrBrainRx vs Ryze Rx

DrBrainRx
Graded #104

Higher grade

vs+12.599999999999994
Ryze Rx
Graded #376

Lower grade

The verdict

DrBrainRx takes it — 70.8/100 to 58.2/100.

DrBrainRx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. DrBrainRx is a neurologist-founded telehealth clinic led by Dr.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueDrBrainRx +22
66
44
Dose & formulationDrBrainRx +8
72
64
Clinical oversightDrBrainRx +12
87
75
Labs & monitoringDrBrainRx +12
64
52
FulfillmentRyze Rx +2
67
69
Contract termsDrBrainRx +20
61
41
DrBrainRx · left barRyze Rx · right bar

The numbers

MetricDrBrainRxRyze Rx
WeighScore70.8/10058.2/100
GradeCC
Scorecard rank#104#376
Semaglutide$199/mo (all doses, compounded)$199/mo (starting dose, 3 month plan, compounded)
Tirzepatide$299/mo (all doses, compounded)$199/mo (starting dose, 3 month plan, compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
DrBrainRx

Graded #104 · C

Strengths

  • Founded and overseen by Dr. Sara Siavoshi — triple board-certified in Neurology, Headache Medicine, and Obesity Medicine
  • LegitScript certified with compounded medications from USP-certified 503B pharmacies
  • Flat-rate pricing — same monthly cost for all dose levels (dose escalation does not raise price)
  • 100% online with rapid approvals (~24-48 hours) and discreet shipping in 3–5 business days
  • Side-effect support, dose adjustments, and injection guides included with provider care

Where it loses points

  • Separate $25/month provider care fee (compounded track) on top of medication cost
  • Compounded medications are not FDA-approved individual drugs
  • Labs not required or included — no baseline bloodwork protocol disclosed
  • States served not published; no explicit list available
  • No dedicated coaching program beyond clinical dose management
Ryze Rx

Graded #376 · C

Strengths

  • Compounded semaglutide and tirzepatide both $199/mo, with $499/$799 three-month bundles
  • Physician consultation, ongoing clinical support and discreet shipping included with each prescription
  • Broad catalog beyond GLP-1: TRT plus peptides (BPC-157, sermorelin, NAD+, retatrutide and more)
  • Free shipping, 24hr prescription turnaround, FSA/HSA eligible; care advertised in all 50 states

Where it loses points

  • Terms, Privacy Policy and HIPAA notice are dead links - no legal entity, refund policy or governing law disclosed
  • Pharmacy partners not named - only 'US-licensed compounding pharmacies'
  • Homepage advertises GLP-1s 'from $149/mo' but the catalog lists $199/mo
  • On-site '4.9/5, 2,400+ reviews' is self-reported, not an independently verified rating

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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