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Head-to-head · WeighScore

Curex vs Signos

Curex
Graded #135

Higher grade

vs+7.800000000000004
Signos
Graded #295

Lower grade

The verdict

Curex takes it — 69.2/100 to 61.4/100.

Curex grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Curex (Curex, Inc.) offers compounded semaglutide ($149/mo) and tirzepatide ($199/mo) in injectable and oral dissolving tablet formats.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueCurex +10
54
44
Dose & formulationCurex +11
75
64
Clinical oversightEven
84
84
Labs & monitoringSignos +16
55
71
FulfillmentCurex +19
90
71
Contract termsCurex +41
61
20
Curex · left barSignos · right bar

The numbers

MetricCurexSignos
WeighScore69.2/10061.4/100
GradeCC
Scorecard rank#135#295
Semaglutide$199/mo (compounded oral)$199/mo (6-month plan, compounded)
Tirzepatide$199/mo (compounded oral)$199/mo (starting dose, compounded)
Coverage45 statesCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualYesInjection only
Curex

Graded #135 · C

Strengths

  • LegitScript certified
  • Named entity (Curex, Inc.) with two offices — Miami FL and NYC
  • No membership fee ever
  • Injectable and oral dissolving tablet formats
  • Third-party lab testing via FDA/DEA certified labs

Where it loses points

  • Not available in AK, AR, CT, HI, MA, NM, MO
  • Compounded only — explicitly states 'We don't prescribe Ozempic, Wegovy, Zepbound, or Mounjaro'
  • Primary business is allergy immunotherapy — GLP-1 is a newer vertical
Signos

Graded #295 · C

Strengths

  • Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
  • Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
  • Free rapid shipping; HSA/FSA eligible
  • Real-time glucose insights and app coaching to help sustain results after GLP-1

Where it loses points

  • Compounded GLP-1s are not FDA-approved finished products
  • Headline price is a 6-month-program rate, not month-to-month
  • Only semaglutide is shown in the program; tirzepatide availability is not confirmed
  • Compounding pharmacy partner and state availability are not published on the landing page

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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