Head-to-head · WeighScore
Cost Plus Drugs vs Velvet Rx
The verdict
Cost Plus Drugs takes it — 58.5/100 to 58.1/100, but only just.
Cost Plus Drugs grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Mark Cuban's transparent-pricing online pharmacy. Velvet Rx is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Cost Plus Drugs | Velvet Rx |
|---|---|---|
| WeighScore | 58.5/100 | 58.1/100 |
| Grade | C | C |
| Scorecard rank | #371 | #381 |
| Semaglutide | $279/mo (brand Ozempic) | $299/mo (compounded) |
| Tirzepatide | Not disclosed | $359/mo (compounded) |
| Coverage | All 50 states | Coverage not published |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Injection only | Yes |
Graded #371 · C
Strengths
- Transparent pricing: wholesale cost + 15% markup + $5 pharmacy fee, the same for everyone
- Around $279/mo for branded Ozempic — well below typical retail list prices
- Mark Cuban's PBM-disrupting pharmacy, praised by Forbes Health, Wired, and KFF Health News
- Ships to all 50 states; genuine FDA-approved Novo Nordisk Ozempic, not compounded
- Partnered with 9amHealth so you can get prescribed and fill at Cost Plus pricing
Where it loses points
- Fulfillment only — no telehealth intake; you need a prescription from an outside clinician
- Ozempic is FDA-indicated for type 2 diabetes, not weight management — weight-loss use is off-label
- Wegovy availability has been spotty — check current stock before assuming it ships
- No compounded semaglutide or tirzepatide — brand only
- No clinical follow-up — side-effect monitoring falls to your prescribing clinician
Graded #381 · C
Strengths
- Public pricing across 3 SKUs (semaglutide $299, tirzepatide $359, oral GLP-1 $349) — uncommon in compounded telehealth
- First-month promo pricing shown upfront ($139 sema / $199 tirz / $189 oral)
- Single monthly price includes consult, prescription, 4 weeks of medication, and free 1–2 day shipping
- FSA/HSA eligible
- Three options under one roof: injectable sema, injectable tirz, and an oral GLP-1
Where it loses points
- Oral GLP-1 SKU doesn't name the specific drug — a real gap given Rybelsus, Foundayo, and compounded oral semaglutide differ clinically
- No LegitScript or NABP .pharmacy seal displayed
- No legal entity name disclosed
- No physical address disclosed
- Compounding pharmacy partner not named
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.