Head-to-head · WeighScore
Cost Plus Drugs vs TRYM Health
The verdict
TRYM Health takes it — 73.8/100 to 58.5/100.
TRYM Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. TRYM Health (TRYM) is a nationwide telehealth service offering compounded GLP-1 weight-loss medication — semaglutide (~$96/mo, $3.20/day) and tirzepatide (~$126/mo, $4.20/day) — as additive-free multi-dose…
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Cost Plus Drugs | TRYM Health |
|---|---|---|
| WeighScore | 58.5/100 | 73.8/100 |
| Grade | C | C |
| Scorecard rank | #371 | #70 |
| Semaglutide | $279/mo (brand Ozempic) | $96/mo (all doses, compounded) |
| Tirzepatide | Not disclosed | $126/mo (all doses, compounded) |
| Coverage | All 50 states | Coverage not published |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #371 · C
Strengths
- Transparent pricing: wholesale cost + 15% markup + $5 pharmacy fee, the same for everyone
- Around $279/mo for branded Ozempic — well below typical retail list prices
- Mark Cuban's PBM-disrupting pharmacy, praised by Forbes Health, Wired, and KFF Health News
- Ships to all 50 states; genuine FDA-approved Novo Nordisk Ozempic, not compounded
- Partnered with 9amHealth so you can get prescribed and fill at Cost Plus pricing
Where it loses points
- Fulfillment only — no telehealth intake; you need a prescription from an outside clinician
- Ozempic is FDA-indicated for type 2 diabetes, not weight management — weight-loss use is off-label
- Wegovy availability has been spotty — check current stock before assuming it ships
- No compounded semaglutide or tirzepatide — brand only
- No clinical follow-up — side-effect monitoring falls to your prescribing clinician
Graded #70 · C
Strengths
- Affordable compounded GLP-1 — semaglutide ~$96/mo ($3.20/day) and tirzepatide ~$126/mo ($4.20/day)
- Available in all 50 states with free shipping and FSA/HSA eligibility
- Multi-dose vials cover all doses up to the maximum; additive-free, with a full starter kit
- Temperature-controlled insulated shipping and flexible cancellation
Where it loses points
- Compounding pharmacy partner not named
- Not LegitScript-certified (no certification displayed)
- Lowest per-day pricing likely requires a longer prepaid plan commitment
- Drugs labeled generically as 'GLP-1' / 'GLP-1 + GIP' on the services page rather than named
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.