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Head-to-head · WeighScore

Cost Plus Drugs vs tru Weight Loss

Cost Plus Drugs
Graded #371

Lower grade

vs+0.3999999999999986
tru Weight Loss
Graded #354

Higher grade

The verdict

tru Weight Loss takes it — 58.9/100 to 58.5/100, but only just.

tru Weight Loss grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. tru Weight Loss (truhealthnow) is a physician-directed telehealth program prescribing compounded semaglutide and tirzepatide, shipped from US-licensed compounding pharmacies. Cost Plus Drugs is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueCost Plus Drugs +7
45
38
Dose & formulationtru Weight Loss +7
65
72
Clinical oversighttru Weight Loss +9
67
76
Labs & monitoringtru Weight Loss +21
51
72
FulfillmentCost Plus Drugs +11
73
62
Contract termsCost Plus Drugs +35
55
20
Cost Plus Drugs · left bartru Weight Loss · right bar

The numbers

MetricCost Plus Drugstru Weight Loss
WeighScore58.5/10058.9/100
GradeCC
Scorecard rank#371#354
Semaglutide$279/mo (brand Ozempic)$299/mo (all doses, 3-month plan, compounded)
TirzepatideNot disclosed$399/mo (all doses, 3-month plan, compounded)
CoverageAll 50 statesCoverage not published
Brand-name accessYesCompounded only
Oral / sublingualInjection onlyInjection only
Cost Plus Drugs

Graded #371 · C

Strengths

  • Transparent pricing: wholesale cost + 15% markup + $5 pharmacy fee, the same for everyone
  • Around $279/mo for branded Ozempic — well below typical retail list prices
  • Mark Cuban's PBM-disrupting pharmacy, praised by Forbes Health, Wired, and KFF Health News
  • Ships to all 50 states; genuine FDA-approved Novo Nordisk Ozempic, not compounded
  • Partnered with 9amHealth so you can get prescribed and fill at Cost Plus pricing

Where it loses points

  • Fulfillment only — no telehealth intake; you need a prescription from an outside clinician
  • Ozempic is FDA-indicated for type 2 diabetes, not weight management — weight-loss use is off-label
  • Wegovy availability has been spotty — check current stock before assuming it ships
  • No compounded semaglutide or tirzepatide — brand only
  • No clinical follow-up — side-effect monitoring falls to your prescribing clinician
tru Weight Loss

Graded #354 · C

Strengths

  • Flat, transparent pricing (299/mo semaglutide, 399/mo tirzepatide)
  • All-inclusive: consult, lab work, medication delivery, nutritionist and behavioral coaching
  • Directed by a named physician (Neha Grover, MD) from a physical clinic

Where it loses points

  • Requires a 3-month commitment before you can cancel
  • States served are not specified and the dispensing pharmacy is not named
  • Does not accept insurance, HSA, or FSA

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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