Head-to-head · WeighScore
Cost Plus Drugs vs Prime Health
The verdict
Prime Health takes it — 59.4/100 to 58.5/100, but only just.
Prime Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Prime Health (joinprimehealth.com) is a LegitScript-certified GLP-1 telehealth platform offering compounded semaglutide and tirzepatide for weight loss. Cost Plus Drugs is close behind and may still be the better fit — see the factor split below.
We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Cost Plus Drugs | Prime Health |
|---|---|---|
| WeighScore | 58.5/100 | 59.4/100 |
| Grade | C | C |
| Scorecard rank | #370 | #344 |
| Semaglutide | $279/mo (brand Ozempic) | $299/mo (compounded) |
| Tirzepatide | Not disclosed | $399/mo (compounded) |
| Coverage | All 50 states | Coverage not published |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #370 · C
Strengths
- Transparent pricing: wholesale cost + 15% markup + $5 pharmacy fee, the same for everyone
- Around $279/mo for branded Ozempic — well below typical retail list prices
- Mark Cuban's PBM-disrupting pharmacy, praised by Forbes Health, Wired, and KFF Health News
- Ships to all 50 states; genuine FDA-approved Novo Nordisk Ozempic, not compounded
- Partnered with 9amHealth so you can get prescribed and fill at Cost Plus pricing
Where it loses points
- Fulfillment only — no telehealth intake; you need a prescription from an outside clinician
- Ozempic is FDA-indicated for type 2 diabetes, not weight management — weight-loss use is off-label
- Wegovy availability has been spotty — check current stock before assuming it ships
- No compounded semaglutide or tirzepatide — brand only
- No clinical follow-up — side-effect monitoring falls to your prescribing clinician
Graded #344 · C
Strengths
- LegitScript-certified platform
- Flat pricing that does not rise as dosage increases
- Bundle includes medication, labs, shipping, and unlimited clinician access
- Money-back guarantee of at least 10% body-weight loss in 4 months
- Fast 24-hour prescription review and 5-7 day delivery
Where it loses points
- Compounded medications only; no FDA-approved brand options listed
- Not available in Louisiana
- Care delivered through third-party clinician groups, not in-house
- Named compounding pharmacy not disclosed
- No insurance accepted
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.