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Head-to-head · WeighScore

Cost Plus Drugs vs PCOS Sisters

Cost Plus Drugs
Graded #371

Lower grade

vs+7.200000000000003
PCOS Sisters
Graded #218

Higher grade

The verdict

PCOS Sisters takes it — 65.7/100 to 58.5/100.

PCOS Sisters grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. PCOS Sisters is a women's telehealth clinic focused on polycystic ovary syndrome that offers a GLP-1 weight and metabolic management program for 150 dollars per month with membership required.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valuePCOS Sisters +16
45
61
Dose & formulationPCOS Sisters +23
65
88
Clinical oversightPCOS Sisters +3
67
70
Labs & monitoringPCOS Sisters +1
51
52
FulfillmentCost Plus Drugs +8
73
65
Contract termsCost Plus Drugs +14
55
41
Cost Plus Drugs · left barPCOS Sisters · right bar

The numbers

MetricCost Plus DrugsPCOS Sisters
WeighScore58.5/10065.7/100
GradeCC
Scorecard rank#371#218
Semaglutide$279/mo (brand Ozempic)$150/mo (plus a separate fee, compounded)
TirzepatideNot disclosed$150/mo (plus a separate fee, compounded)
CoverageAll 50 states12 states
Brand-name accessYesYes
Oral / sublingualInjection onlyYes
Cost Plus Drugs

Graded #371 · C

Strengths

  • Transparent pricing: wholesale cost + 15% markup + $5 pharmacy fee, the same for everyone
  • Around $279/mo for branded Ozempic — well below typical retail list prices
  • Mark Cuban's PBM-disrupting pharmacy, praised by Forbes Health, Wired, and KFF Health News
  • Ships to all 50 states; genuine FDA-approved Novo Nordisk Ozempic, not compounded
  • Partnered with 9amHealth so you can get prescribed and fill at Cost Plus pricing

Where it loses points

  • Fulfillment only — no telehealth intake; you need a prescription from an outside clinician
  • Ozempic is FDA-indicated for type 2 diabetes, not weight management — weight-loss use is off-label
  • Wegovy availability has been spotty — check current stock before assuming it ships
  • No compounded semaglutide or tirzepatide — brand only
  • No clinical follow-up — side-effect monitoring falls to your prescribing clinician
PCOS Sisters

Graded #218 · C

Strengths

  • Dedicated PCOS specialty model with metabolic program and fitness app included
  • Transparent 150 dollars per month GLP-1 management fee
  • Names real partner pharmacies (Strive, Striker) and lists phone support

Where it loses points

  • Only 12 states served
  • Membership required on top of the medical program
  • Unclear whether pharmacy dispensing fees are separate from the 150/mo fee

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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