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Head-to-head · WeighScore

Cost Plus Drugs vs LifespanningRx

Cost Plus Drugs
Graded #371

Lower grade

vs+1.8999999999999986
LifespanningRx
Graded #324

Higher grade

The verdict

LifespanningRx takes it — 60.4/100 to 58.5/100, but only just.

LifespanningRx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. LifespanningRx is a clinician-guided longevity and peptide telehealth brand whose Weight Loss Program prescribes compounded GLP-1 (semaglutide/tirzepatide) injectables alongside peptide and healthy-aging… Cost Plus Drugs is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueEven
45
45
Dose & formulationCost Plus Drugs +12
65
53
Clinical oversightLifespanningRx +14
67
81
Labs & monitoringLifespanningRx +2
51
53
FulfillmentLifespanningRx +10
73
83
Contract termsEven
55
55
Cost Plus Drugs · left barLifespanningRx · right bar

The numbers

MetricCost Plus DrugsLifespanningRx
WeighScore58.5/10060.4/100
GradeCC
Scorecard rank#371#324
Semaglutide$279/mo (brand Ozempic)Not disclosed
TirzepatideNot disclosedNot disclosed
CoverageAll 50 statesAll 50 states
Brand-name accessYesYes
Oral / sublingualInjection onlyInjection only
Cost Plus Drugs

Graded #371 · C

Strengths

  • Transparent pricing: wholesale cost + 15% markup + $5 pharmacy fee, the same for everyone
  • Around $279/mo for branded Ozempic — well below typical retail list prices
  • Mark Cuban's PBM-disrupting pharmacy, praised by Forbes Health, Wired, and KFF Health News
  • Ships to all 50 states; genuine FDA-approved Novo Nordisk Ozempic, not compounded
  • Partnered with 9amHealth so you can get prescribed and fill at Cost Plus pricing

Where it loses points

  • Fulfillment only — no telehealth intake; you need a prescription from an outside clinician
  • Ozempic is FDA-indicated for type 2 diabetes, not weight management — weight-loss use is off-label
  • Wegovy availability has been spotty — check current stock before assuming it ships
  • No compounded semaglutide or tirzepatide — brand only
  • No clinical follow-up — side-effect monitoring falls to your prescribing clinician
LifespanningRx

Graded #324 · C

Strengths

  • Compounded GLP-1 (semaglutide/tirzepatide) weight-loss program with licensed clinicians included
  • LegitScript-certified and HIPAA-compliant; works with 503A/503B licensed US pharmacies
  • Longevity and peptide protocols alongside weight loss; free membership, no monthly fee
  • Discreet nationwide shipping with 24/365 support
  • Also a turnkey white-label platform for clinics and wellness brands to launch programs

Where it loses points

  • Exact dosing and pricing are shown only after completing the patient assessment
  • Compounded GLP-1s are not FDA-approved finished products
  • States served are not publicly listed
  • Part B2B/white-label, so the consumer experience can vary by partnered clinic

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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