Head-to-head · WeighScore
Cost Plus Drugs vs LifeRx.md
The verdict
LifeRx.md takes it — 69.3/100 to 58.5/100.
LifeRx.md grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. LifeRx.md is a LegitScript-certified US telehealth provider offering customized weight loss with GLP-1s.
We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Cost Plus Drugs | LifeRx.md |
|---|---|---|
| WeighScore | 58.5/100 | 69.3/100 |
| Grade | C | C |
| Scorecard rank | #370 | #127 |
| Semaglutide | $279/mo (brand Ozempic) | $200/mo |
| Tirzepatide | Not disclosed | $275/mo |
| Coverage | All 50 states | All 50 states |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #370 · C
Strengths
- Transparent pricing: wholesale cost + 15% markup + $5 pharmacy fee, the same for everyone
- Around $279/mo for branded Ozempic — well below typical retail list prices
- Mark Cuban's PBM-disrupting pharmacy, praised by Forbes Health, Wired, and KFF Health News
- Ships to all 50 states; genuine FDA-approved Novo Nordisk Ozempic, not compounded
- Partnered with 9amHealth so you can get prescribed and fill at Cost Plus pricing
Where it loses points
- Fulfillment only — no telehealth intake; you need a prescription from an outside clinician
- Ozempic is FDA-indicated for type 2 diabetes, not weight management — weight-loss use is off-label
- Wegovy availability has been spotty — check current stock before assuming it ships
- No compounded semaglutide or tirzepatide — brand only
- No clinical follow-up — side-effect monitoring falls to your prescribing clinician
Graded #127 · C
Strengths
- Flat pricing that does not rise with dose: semaglutide ~$200, tirzepatide ~$275 per 5-week supply
- LegitScript certified; prescriptions filled by state-licensed 503A pharmacies
- Available in all 50 states
- HSA and FSA payments accepted
- Required video telehealth consult ensures clinician oversight
Where it loses points
- Compounded GLP-1s are not FDA-approved for safety, efficacy or quality
- Extra fees stack up: ~$30 shipping, $49.95 initial consult, $25 follow-ups
- True monthly cost (~$255) is higher than the headline medication price
- Specific list of supported states not enumerated on site
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.