Head-to-head · WeighScore
Cost Plus Drugs vs Harmony Wellness Clinic
The verdict
Harmony Wellness Clinic takes it — 60.9/100 to 58.5/100.
Harmony Wellness Clinic grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Harmony Wellness Clinic is a LegitScript-certified telehealth platform offering compounded semaglutide (GLP-1 + B12) and compounded tirzepatide (GLP-1/GIP + B12) for medically supervised weight loss.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Cost Plus Drugs | Harmony Wellness Clinic |
|---|---|---|
| WeighScore | 58.5/100 | 60.9/100 |
| Grade | C | C |
| Scorecard rank | #370 | #308 |
| Semaglutide | $279/mo (brand Ozempic) | $200/mo (starting dose, compounded) |
| Tirzepatide | Not disclosed | $250/mo (starting dose, compounded) |
| Coverage | All 50 states | 36 states |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #370 · C
Strengths
- Transparent pricing: wholesale cost + 15% markup + $5 pharmacy fee, the same for everyone
- Around $279/mo for branded Ozempic — well below typical retail list prices
- Mark Cuban's PBM-disrupting pharmacy, praised by Forbes Health, Wired, and KFF Health News
- Ships to all 50 states; genuine FDA-approved Novo Nordisk Ozempic, not compounded
- Partnered with 9amHealth so you can get prescribed and fill at Cost Plus pricing
Where it loses points
- Fulfillment only — no telehealth intake; you need a prescription from an outside clinician
- Ozempic is FDA-indicated for type 2 diabetes, not weight management — weight-loss use is off-label
- Wegovy availability has been spotty — check current stock before assuming it ships
- No compounded semaglutide or tirzepatide — brand only
- No clinical follow-up — side-effect monitoring falls to your prescribing clinician
Graded #308 · C
Strengths
- LegitScript certified with licensed APRN-CNP clinical oversight by Kristina Stout
- Two compounded GLP-1 options: semaglutide+B12 (5 dose levels) and tirzepatide+B12 (6 dose levels)
- Partners with four named 503A compounding pharmacies for a transparent supply chain
- Competitive starting prices: $200/month for semaglutide and $250/month for tirzepatide
- Telehealth services available in 36 states via the Optimantra online patient portal
Where it loses points
- 36-state coverage — many states including some large markets not served
- Care led by APRN-CNP, not an MD or DO; no physician name disclosed
- Pricing scales with dose level up to $300/month (sema) and $450/month (tirz)
- Labs not mentioned or included on any public page — baseline bloodwork protocol unknown
- No coaching or lifestyle program disclosed beyond clinical dose management
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.