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Head-to-head · WeighScore

Coby Health vs Signos

Coby Health
Graded #210

Higher grade

vs+4.600000000000001
Signos
Graded #293

Lower grade

The verdict

Coby Health takes it — 66/100 to 61.4/100.

Coby Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Chicago/Springfield IL DTC telehealth marketplace (Coby Health LLC, BBB file opened 3/2025) offering compounded semaglutide from $99/mo (6-mo bundle, 0.25mg) and compounded tirzepatide from $179/mo (6-mo…

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueCoby Health +20
64
44
Dose & formulationSignos +10
54
64
Clinical oversightSignos +3
81
84
Labs & monitoringSignos +16
55
71
FulfillmentCoby Health +15
86
71
Contract termsCoby Health +35
55
20
Coby Health · left barSignos · right bar

The numbers

MetricCoby HealthSignos
WeighScore66/10061.4/100
GradeCC
Scorecard rank#210#293
Semaglutide$159/mo (0.25 mg dose, compounded)$199/mo (6-month plan, compounded)
Tirzepatide$239/mo (2.5 mg dose, compounded)$199/mo (starting dose, compounded)
Coverage46 statesCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
Coby Health

Graded #210 · C

Strengths

  • LegitScript Certified (seal 38387067)
  • No membership fee
  • Aggressive 6-month bundle pricing
  • Beluga Health P.A. clinical network — board-certified, 50-state licensure
  • Trustpilot 4.9/5 (~83 reviews)

Where it loses points

  • Does NOT publicly name compounding pharmacy partner(s) — transparency gap vs Belle/Joi+Blokes
  • Compounded medications are not FDA-approved
  • Tirzepatide pricing escalates steeply ($439/mo at 15mg monthly)
  • $50 non-refundable cancellation fee
  • No oral GLP-1 options
Signos

Graded #293 · C

Strengths

  • Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
  • Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
  • Free rapid shipping; HSA/FSA eligible
  • Real-time glucose insights and app coaching to help sustain results after GLP-1

Where it loses points

  • Compounded GLP-1s are not FDA-approved finished products
  • Headline price is a 6-month-program rate, not month-to-month
  • Only semaglutide is shown in the program; tirzepatide availability is not confirmed
  • Compounding pharmacy partner and state availability are not published on the landing page

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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