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Head-to-head · WeighScore

CLYR Health vs LillyDirect Foundayo

CLYR Health
Graded #275

Lower grade

vs+5
LillyDirect Foundayo
Graded #165

Higher grade

The verdict

LillyDirect Foundayo takes it — 67.2/100 to 62.2/100.

LillyDirect Foundayo grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Eli Lilly's manufacturer direct-pay channel for Foundayo (orforglipron), the first oral GLP-1 pill for weight loss.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueLillyDirect Foundayo +33
39
72
Dose & formulationCLYR Health +29
88
59
Clinical oversightLillyDirect Foundayo +4
74
78
Labs & monitoringEven
52
52
FulfillmentLillyDirect Foundayo +3
77
80
Contract termsLillyDirect Foundayo +18
37
55
CLYR Health · left barLillyDirect Foundayo · right bar

The numbers

MetricCLYR HealthLillyDirect Foundayo
WeighScore62.2/10067.2/100
GradeCC
Scorecard rank#275#165
Semaglutide$229/mo (compounded)Not disclosed
Tirzepatide$249/mo (compounded)Not disclosed
CoverageCoverage not publishedAll 50 states
Brand-name accessYesYes
Oral / sublingualYesYes
CLYR Health

Graded #275 · C

Strengths

  • Flat 'any dose, one price' billing so the monthly cost does not rise as your dose climbs
  • LegitScript Certified with a named 503A pharmacy partner (The Pharmacy Hub, Miami FL) and MD Integrations clinicians
  • 3-month prepay drops semaglutide to $189/mo and tirzepatide to $199/mo

Where it loses points

  • State availability gated behind intake; not published on the marketing site
  • Standing monthly rates ($229-249) run above the cheapest compounded competitors
  • Broad catalog (weight loss, sexual health, longevity) rather than a weight-loss specialist
LillyDirect Foundayo

Graded #165 · C

Strengths

  • Cheapest legal path to a brand-name GLP-1 in 2026 ($25/mo with savings card for commercial insurance)
  • Direct from manufacturer — no compounding, no third-party reseller
  • Daily oral pill, no injections, no refrigeration
  • Available in all 50 states

Where it loses points

  • Lower mean weight loss vs Wegovy (14.9%) and Zepbound (20.9%) — labeled-dose 11.1% per Foundayo PI
  • Requires existing prescription from a separate prescriber (LillyDirect does not write the prescription)
  • $25 savings card requires commercial insurance — Medicare and Medicaid not eligible
  • Strict empty-stomach 30-minute window may be hard for some patients to follow

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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