Skip to content
GLP-1 Scorecard
Menu

Head-to-head · WeighScore

CLYR Health vs Defy Medical

CLYR Health
Graded #275

Higher grade

vs+2
Defy Medical
Graded #325

Lower grade

The verdict

CLYR Health takes it — 62.2/100 to 60.2/100, but only just.

CLYR Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. CLYR Health is a Florida-based telehealth pharmacy offering compounded GLP-1 weight-loss injections alongside sexual-health, longevity and wellness treatments. Defy Medical is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueDefy Medical +6
39
45
Dose & formulationCLYR Health +32
88
56
Clinical oversightDefy Medical +6
74
80
Labs & monitoringDefy Medical +13
52
65
FulfillmentCLYR Health +14
77
63
Contract termsDefy Medical +18
37
55
CLYR Health · left barDefy Medical · right bar

The numbers

MetricCLYR HealthDefy Medical
WeighScore62.2/10060.2/100
GradeCC
Scorecard rank#275#325
Semaglutide$229/mo (compounded)Not disclosed
Tirzepatide$249/mo (compounded)Not disclosed
CoverageCoverage not publishedCoverage not published
Brand-name accessYesCompounded only
Oral / sublingualYesYes
CLYR Health

Graded #275 · C

Strengths

  • Flat 'any dose, one price' billing so the monthly cost does not rise as your dose climbs
  • LegitScript Certified with a named 503A pharmacy partner (The Pharmacy Hub, Miami FL) and MD Integrations clinicians
  • 3-month prepay drops semaglutide to $189/mo and tirzepatide to $199/mo

Where it loses points

  • State availability gated behind intake; not published on the marketing site
  • Standing monthly rates ($229-249) run above the cheapest compounded competitors
  • Broad catalog (weight loss, sexual health, longevity) rather than a weight-loss specialist
Defy Medical

Graded #325 · C

Strengths

  • Multiple GLP-1 options: semaglutide, tirzepatide, liraglutide
  • Offers injection, ODT, and oral drop delivery forms
  • Comprehensive blood testing and named medical director
  • Established clinic with strong Trustpilot review volume

Where it loses points

  • GLP-1 pricing not published on the website
  • States served and shipping limits not disclosed
  • Compounded versus brand status not stated online
  • Lab-heavy, consult-first model may cost more upfront

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

← Back to the scorecard