Head-to-head · WeighScore
Clinic Secret vs SkyRx
The verdict
Clinic Secret takes it — 61.1/100 to 58.9/100.
Clinic Secret grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Clinic Secret (clinicsecret.com), launched late 2025, is a functioning US GLP-1 telehealth platform offering compounded semaglutide and tirzepatide for weight loss, plus a pentadeca arginate peptide.
We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Clinic Secret | SkyRx |
|---|---|---|
| WeighScore | 61.1/100 | 58.9/100 |
| Grade | C | C |
| Scorecard rank | #301 | #355 |
| Semaglutide | $196/mo (starting dose, compounded) | $199/mo (all doses, 12-month plan, compounded) |
| Tirzepatide | $196/mo (compounded) | Not disclosed |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Yes |
Graded #301 · C
Strengths
- Low entry price starting at $49/week with no membership fees
- Monthly price does not increase as dosage rises
- Fast nationwide shipping in about three days
- Asynchronous intake available in some states (no required video call)
- Money-back guarantee tied to weight-loss goals
Where it loses points
- Newly launched (late 2025); limited independent track record
- Compounded medications only; no FDA-approved brand options
- Named compounding pharmacy not disclosed
- State availability not published
- No insurance accepted
Graded #355 · C
Strengths
- All-inclusive 199 dollars per month covers medication, supplies, doctor visit and shipping
- Offers both injectable and oral semaglutide, dispensed by FDA-registered 503B pharmacies
- Same-day shipping for orders before 2pm ET in temperature-controlled packaging
Where it loses points
- 199 dollars pricing requires a 12-month subscription paid upfront
- Tirzepatide only listed as coming soon
- GLP-1s not yet available in all 50 states; specific states not listed
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.