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Head-to-head · WeighScore

Clinic Secret vs Onyx Weight Loss

Clinic Secret
Graded #301

Higher grade

vs+2.3000000000000043
Onyx Weight Loss
Graded #359

Lower grade

The verdict

Clinic Secret takes it — 61.1/100 to 58.8/100.

Clinic Secret grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Clinic Secret (clinicsecret.com), launched late 2025, is a functioning US GLP-1 telehealth platform offering compounded semaglutide and tirzepatide for weight loss, plus a pentadeca arginate peptide.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueClinic Secret +12
55
43
Dose & formulationEven
64
64
Clinical oversightOnyx Weight Loss +1
74
75
Labs & monitoringOnyx Weight Loss +11
52
63
FulfillmentClinic Secret +6
59
53
Contract termsClinic Secret +6
61
55
Clinic Secret · left barOnyx Weight Loss · right bar

The numbers

MetricClinic SecretOnyx Weight Loss
WeighScore61.1/10058.8/100
GradeCC
Scorecard rank#301#359
Semaglutide$196/mo (starting dose, compounded)$228/mo (starting dose, compounded)
Tirzepatide$196/mo (compounded)$280/mo (starting dose, compounded)
CoverageCoverage not published8 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
Clinic Secret

Graded #301 · C

Strengths

  • Low entry price starting at $49/week with no membership fees
  • Monthly price does not increase as dosage rises
  • Fast nationwide shipping in about three days
  • Asynchronous intake available in some states (no required video call)
  • Money-back guarantee tied to weight-loss goals

Where it loses points

  • Newly launched (late 2025); limited independent track record
  • Compounded medications only; no FDA-approved brand options
  • Named compounding pharmacy not disclosed
  • State availability not published
  • No insurance accepted
Onyx Weight Loss

Graded #359 · C

Strengths

  • Competitive entry pricing: semaglutide from $228/mo and tirzepatide from $280/mo with medication + supplies included
  • Nurse-practitioner-led care: founder Tasha Vangile FNP-C (20+ years) and Stephanie Robison APRN-CNP (27 years experience)
  • Low-cost $99/mo GLP-1 microdosing option for patients who prefer a gradual titration start
  • Strive Pharmacy partnership implies compounded 503A-quality supply chain from a known pharmacy
  • Multi-modal clinic: GLP-1 + peptides + HRT + nutrition coaching available under one provider team

Where it loses points

  • Only 8 states (NC, CO, ME, VT, VA, IA, NH, PA) — excludes the majority of the US
  • No LegitScript certification; credentialing evidence limited to local 2025 Best of Iredell award
  • Specific drug names (semaglutide/tirzepatide) never stated on website; compounded status inferred, not disclosed
  • Labs not included or mentioned; no baseline bloodwork protocol published
  • Pricing shown as 'Starting at' with no dose-escalation tier pricing disclosed publicly

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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