Head-to-head · WeighScore
Clinic Secret vs Defy Medical
The verdict
Clinic Secret takes it — 60.9/100 to 60.2/100, but only just.
Clinic Secret grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Clinic Secret (clinicsecret.com), launched late 2025, is a functioning US GLP-1 telehealth platform offering compounded semaglutide and tirzepatide for weight loss, plus a pentadeca arginate peptide. Defy Medical is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Clinic Secret | Defy Medical |
|---|---|---|
| WeighScore | 60.9/100 | 60.2/100 |
| Grade | C | C |
| Scorecard rank | #308 | #326 |
| Semaglutide | $196/mo (starting dose, compounded) | Not disclosed |
| Tirzepatide | $196/mo (compounded) | Not disclosed |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Yes |
Graded #308 · C
Strengths
- Low entry price starting at $49/week with no membership fees
- Monthly price does not increase as dosage rises
- Fast nationwide shipping in about three days
- Asynchronous intake available in some states (no required video call)
- Money-back guarantee tied to weight-loss goals
Where it loses points
- Newly launched (late 2025); limited independent track record
- Compounded medications only; no FDA-approved brand options
- Named compounding pharmacy not disclosed
- State availability not published
- No insurance accepted
Graded #326 · C
Strengths
- Multiple GLP-1 options: semaglutide, tirzepatide, liraglutide
- Offers injection, ODT, and oral drop delivery forms
- Comprehensive blood testing and named medical director
- Established clinic with strong Trustpilot review volume
Where it loses points
- GLP-1 pricing not published on the website
- States served and shipping limits not disclosed
- Compounded versus brand status not stated online
- Lab-heavy, consult-first model may cost more upfront
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.