Head-to-head · WeighScore
Calibrate Health vs Trillium Meds
The verdict
Trillium Meds takes it — 69.4/100 to 69.3/100, but only just.
Trillium Meds grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Trillium Meds is a small, owner-operated telehealth platform based in Portland, OR that connects patients with independent licensed providers and FDA-registered compounding pharmacies for compounded… Calibrate Health is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Calibrate Health | Trillium Meds |
|---|---|---|
| WeighScore | 69.3/100 | 69.4/100 |
| Grade | C | C |
| Scorecard rank | #132 | #130 |
| Semaglutide | Not disclosed | $119/mo (3-month plan, compounded) |
| Tirzepatide | Not disclosed | $199/mo (3-month plan, compounded) |
| Coverage | All 50 states | All 50 states |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #132 · C
Strengths
- Year-long program with 1:1 video coaching, dietitian support, and behavior-change curriculum — a deeper clinical wrap than transactional telehealth
- $199/month program fee is competitive; medication co-pay can drop to ~$25/month with insurance and a manufacturer savings card
- Branded GLP-1s only (Wegovy, Ozempic, Zepbound, Foundayo) — no compounded products
- Insurance navigation team works to maximize coverage and reportedly accepts most major commercial plans
- Money-back guarantee tied to a 10% weight-loss outcome over the program year
Where it loses points
- Medication cost is on top of the $199/month fee; cash-pay patients face full manufacturer pricing
- Insurance navigation only helps if your plan actually covers branded GLP-1s for weight loss — many don't
- Meaningfully more expensive than compounded telehealth if your insurance denies coverage
- Distinct from 'Oxford's Medical Weight Loss (The Calibrate Clinic)' — don't confuse the two
- Initial 3-month commitment required ($597 total, billed as $199/mo) before it renews month-to-month — more lock-in than month-to-month rivals
Graded #130 · C
Strengths
- LegitScript certified with an active seal; serves all 50 states plus Puerto Rico with no geographic restrictions
- All-inclusive pricing covers medication, provider consultation, and shipping with no hidden fees or add-ons
- Two pharmacy options (BPI Labs with B6, ProRx) and three plan structures: 1-month, 3-month fixed, or 3-month titrated
- Small owner-operated; founder personally handles customer support outside business hours for direct, responsive service
- Klarna and Affirm financing available; pause anytime with no long-term commitment required
Where it loses points
- No labs, coaching, or clinical monitoring included — telehealth Rx and pharmacy fulfillment only
- Small single-operator platform may limit capacity and support consistency as patient volume grows
- Compounded medications are not FDA-approved; newer platform with limited long-term public track record
- Tirzepatide from $199/mo (3-mo plan) is mid-market; sema from $119/mo competitive but not lowest available
- No live video consult disclosed; async intake-form-based provider review by external licensed provider network
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.