Head-to-head · WeighScore
Calibrate Health vs Synergy Rx
The verdict
Synergy Rx takes it — 76.2/100 to 69.3/100.
Synergy Rx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Brand Wegovy, Ozempic or Mounjaro when clinically appropriate, with unlimited round-the-clock clinical contact.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Calibrate Health | Synergy Rx |
|---|---|---|
| WeighScore | 69.3/100 | 76.2/100 |
| Grade | C | C |
| Scorecard rank | #125 | #41 |
| Semaglutide | Not disclosed | From $199/mo |
| Tirzepatide | Not disclosed | From $349/mo |
| Coverage | All 50 states | Not disclosed |
| Brand-name access | Yes | Yes |
| Oral / sublingual | Injection only | Injection only |
Graded #125 · C
Strengths
- Year-long program with 1:1 video coaching, dietitian support, and behavior-change curriculum — a deeper clinical wrap than transactional telehealth
- $199/month program fee is competitive; medication co-pay can drop to ~$25/month with insurance and a manufacturer savings card
- Branded GLP-1s only (Wegovy, Ozempic, Zepbound, Foundayo) — no compounded products
- Insurance navigation team works to maximize coverage and reportedly accepts most major commercial plans
- Money-back guarantee tied to a 10% weight-loss outcome over the program year
Where it loses points
- Medication cost is on top of the $199/month fee; cash-pay patients face full manufacturer pricing
- Insurance navigation only helps if your plan actually covers branded GLP-1s for weight loss — many don't
- Meaningfully more expensive than compounded telehealth if your insurance denies coverage
- Distinct from 'Oxford's Medical Weight Loss (The Calibrate Clinic)' — don't confuse the two
- Initial 3-month commitment required ($597 total, billed as $199/mo) before it renews month-to-month — more lock-in than month-to-month rivals
Graded #41 · C
Strengths
- Prescribes FDA-approved brand Wegovy, Ozempic and Mounjaro when clinically appropriate
- Unlimited appointments, unlimited messaging and 24/7 access to a dedicated clinical team
- $100 welcome credit at checkout, and FSA/HSA eligible
Where it loses points
- Publishes no GLP-1 price anywhere on its own site
- At $349/mo tirzepatide sits roughly $100 above the compounded median we track
- Does not publish which states it serves
- No published cancellation or refund terms
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.