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Head-to-head · WeighScore

Calibrate Health vs DrBrainRx

Calibrate Health
Graded #133

Lower grade

vs+1.5
DrBrainRx
Graded #104

Higher grade

The verdict

DrBrainRx takes it — 70.8/100 to 69.3/100, but only just.

DrBrainRx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. DrBrainRx is a neurologist-founded telehealth clinic led by Dr. Calibrate Health is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueDrBrainRx +21
45
66
Dose & formulationDrBrainRx +19
53
72
Clinical oversightCalibrate Health +7
94
87
Labs & monitoringCalibrate Health +24
88
64
FulfillmentCalibrate Health +25
92
67
Contract termsDrBrainRx +6
55
61
Calibrate Health · left barDrBrainRx · right bar

The numbers

MetricCalibrate HealthDrBrainRx
WeighScore69.3/10070.8/100
GradeCC
Scorecard rank#133#104
SemaglutideNot disclosed$199/mo (all doses, compounded)
TirzepatideNot disclosed$299/mo (all doses, compounded)
CoverageAll 50 statesCoverage not published
Brand-name accessYesCompounded only
Oral / sublingualInjection onlyInjection only
Calibrate Health

Graded #133 · C

Strengths

  • Year-long program with 1:1 video coaching, dietitian support, and behavior-change curriculum — a deeper clinical wrap than transactional telehealth
  • $199/month program fee is competitive; medication co-pay can drop to ~$25/month with insurance and a manufacturer savings card
  • Branded GLP-1s only (Wegovy, Ozempic, Zepbound, Foundayo) — no compounded products
  • Insurance navigation team works to maximize coverage and reportedly accepts most major commercial plans
  • Money-back guarantee tied to a 10% weight-loss outcome over the program year

Where it loses points

  • Medication cost is on top of the $199/month fee; cash-pay patients face full manufacturer pricing
  • Insurance navigation only helps if your plan actually covers branded GLP-1s for weight loss — many don't
  • Meaningfully more expensive than compounded telehealth if your insurance denies coverage
  • Distinct from 'Oxford's Medical Weight Loss (The Calibrate Clinic)' — don't confuse the two
  • Initial 3-month commitment required ($597 total, billed as $199/mo) before it renews month-to-month — more lock-in than month-to-month rivals
DrBrainRx

Graded #104 · C

Strengths

  • Founded and overseen by Dr. Sara Siavoshi — triple board-certified in Neurology, Headache Medicine, and Obesity Medicine
  • LegitScript certified with compounded medications from USP-certified 503B pharmacies
  • Flat-rate pricing — same monthly cost for all dose levels (dose escalation does not raise price)
  • 100% online with rapid approvals (~24-48 hours) and discreet shipping in 3–5 business days
  • Side-effect support, dose adjustments, and injection guides included with provider care

Where it loses points

  • Separate $25/month provider care fee (compounded track) on top of medication cost
  • Compounded medications are not FDA-approved individual drugs
  • Labs not required or included — no baseline bloodwork protocol disclosed
  • States served not published; no explicit list available
  • No dedicated coaching program beyond clinical dose management

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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