Head-to-head · WeighScore
Bionomy Health vs Cost Plus Drugs
The verdict
Bionomy Health takes it — 73.6/100 to 58.5/100.
Bionomy Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Bionomy Health is a physician-led, direct-to-consumer men's telehealth brand offering compounded GLP-1 weight-loss medication alongside testosterone, peptides, and longevity protocols.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Bionomy Health | Cost Plus Drugs |
|---|---|---|
| WeighScore | 73.6/100 | 58.5/100 |
| Grade | C | C |
| Scorecard rank | #71 | #371 |
| Semaglutide | $189/mo | $279/mo (brand Ozempic) |
| Tirzepatide | $249/mo | Not disclosed |
| Coverage | 48 states | All 50 states |
| Brand-name access | Yes | Yes |
| Oral / sublingual | Injection only | Injection only |
Graded #71 · C
Strengths
- Offers both compounded semaglutide (189/mo) and tirzepatide (249/mo) with pay-per-prescription pricing and no subscription
- Physician-led with a free, physician-reviewed intake before you pay anything
- Fills through LegitScript-certified compounding pharmacies Strive and Absolute; available in 48 states
- Pairs GLP-1 protocols with muscle-preserve supplements and a written training note to protect lean mass
Where it loses points
- Men's health brand, so the site framing and protocols are geared to men rather than a general audience
- New brand launched in 2026 with limited independent reviews and track record
- Not available in Alaska or Hawaii; compounded medications are not FDA-approved
Graded #371 · C
Strengths
- Transparent pricing: wholesale cost + 15% markup + $5 pharmacy fee, the same for everyone
- Around $279/mo for branded Ozempic — well below typical retail list prices
- Mark Cuban's PBM-disrupting pharmacy, praised by Forbes Health, Wired, and KFF Health News
- Ships to all 50 states; genuine FDA-approved Novo Nordisk Ozempic, not compounded
- Partnered with 9amHealth so you can get prescribed and fill at Cost Plus pricing
Where it loses points
- Fulfillment only — no telehealth intake; you need a prescription from an outside clinician
- Ozempic is FDA-indicated for type 2 diabetes, not weight management — weight-loss use is off-label
- Wegovy availability has been spotty — check current stock before assuming it ships
- No compounded semaglutide or tirzepatide — brand only
- No clinical follow-up — side-effect monitoring falls to your prescribing clinician
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.