Head-to-head · WeighScore
Big Easy Weight Loss vs Signos
The verdict
Big Easy Weight Loss takes it — 75.3/100 to 61.4/100.
Big Easy Weight Loss grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Big Easy Weight Loss (joinbigeasy.com) is a New Orleans MD-run telehealth that ships compounded GLP-1 medication nationwide.
We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Big Easy Weight Loss | Signos |
|---|---|---|
| WeighScore | 75.3/100 | 61.4/100 |
| Grade | C | C |
| Scorecard rank | #56 | #293 |
| Semaglutide | $133/mo (all doses, compounded) | $199/mo (6-month plan, compounded) |
| Tirzepatide | $166/mo (all doses, compounded) | $199/mo (starting dose, compounded) |
| Coverage | All 50 states | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #56 · C
Strengths
- Low pricing: about 133 dollars per month for semaglutide, 166 for tirzepatide
- Site states it serves all 50 states with a 2 to 3 day pharmacy turnaround
- Names its partner compounding pharmacies and a Chief Medical Officer
Where it loses points
- Priced as 10 to 12-week packages rather than a simple monthly fee
- New-patient pricing is promotional and may rise on renewal
Graded #293 · C
Strengths
- Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
- Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
- Free rapid shipping; HSA/FSA eligible
- Real-time glucose insights and app coaching to help sustain results after GLP-1
Where it loses points
- Compounded GLP-1s are not FDA-approved finished products
- Headline price is a 6-month-program rate, not month-to-month
- Only semaglutide is shown in the program; tirzepatide availability is not confirmed
- Compounding pharmacy partner and state availability are not published on the landing page
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.