Head-to-head · WeighScore
BetterMe Rx vs Signos
The verdict
BetterMe Rx takes it — 64.9/100 to 61.4/100.
BetterMe Rx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. BetterMe Rx offers compounded semaglutide ($199/mo) and tirzepatide ($299/mo) in both injectable and oral daily tablet formats.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | BetterMe Rx | Signos |
|---|---|---|
| WeighScore | 64.9/100 | 61.4/100 |
| Grade | C | C |
| Scorecard rank | #230 | #293 |
| Semaglutide | $199/mo (promotional rate, compounded) | $199/mo (6-month plan, compounded) |
| Tirzepatide | $299/mo (promotional rate, compounded) | $199/mo (starting dose, compounded) |
| Coverage | All 50 states | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Injection only |
Graded #230 · C
Strengths
- LegitScript verified
- All 50 states coverage
- Six named pharmacy partners with phone numbers — exceptional transparency
- Both injectable and oral daily tablet formats for sema and tirz
- Multi-month discounts (3-month and 6-month plans)
Where it loses points
- No formal corporate entity name or address disclosed
- Compounded only — no brand-name options
- Broader platform (HRT, ED, NAD+, Sermorelin, skincare)
- Headline $199/$299 are limited-time SALE prices; regular prices are $249/$349 per month
Graded #293 · C
Strengths
- Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
- Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
- Free rapid shipping; HSA/FSA eligible
- Real-time glucose insights and app coaching to help sustain results after GLP-1
Where it loses points
- Compounded GLP-1s are not FDA-approved finished products
- Headline price is a 6-month-program rate, not month-to-month
- Only semaglutide is shown in the program; tirzepatide availability is not confirmed
- Compounding pharmacy partner and state availability are not published on the landing page
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.