Head-to-head · WeighScore
Avono Health vs Direct Meds
By GLP-1 ScorecardUpdated
Score comparison
Direct Meds has the higher recorded score — 77.6/100 to 58.7/100.
Direct Meds grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Direct Meds prices compounded injections and sublingual bottles separately; compare the renewal charge and early cancellation cutoff before choosing a plan.
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Factor by factor
These are recorded editorial marks, not a measure of clinical outcomes. Current prices and terms may differ from those used in the marks. See the methodology.
The numbers
Swipe or scroll to compare both providers.
| Metric | Avono Health | Direct Meds |
|---|---|---|
| WeighScore | 58.7/100 | 77.6/100 |
| Grade | C | C+ |
| Site position | #411 | #35 |
| Semaglutide | $269/mo (compounded) | $249/30 days sublingual · $297/mo injectable |
| Tirzepatide | $349/mo (compounded) | $299/30 days sublingual · $399/mo injectable |
| Coverage | Coverage not published | Not publicly listed |
| Brand-name access | Not confirmed | Not confirmed |
| Oral / sublingual | Yes | Yes |
Site position #411 · C
Strengths
- Transparent tiered pricing from $179/mo (microdose semaglutide injection)
- Full compounded range — semaglutide and tirzepatide, injection and oral, microdose and standard
- Free and discreet shipping; 24/7/365 messaging support; 100% online
- US-licensed clinicians and pharmacies; bundle discounts at 3/6/12 months
What to consider
- Medications are compounded, not FDA-approved brand-name
- Compounding pharmacy not publicly named
- State availability not published
- Newer brand with limited independent review history
Site position #35 · C+
FDAWarning letter issued to directmeds.com, Inc. dba DirectMeds in September 2025. See the FDA warning-letter database.
Strengths
- Injection and sublingual preparations have separately published prices
- Pricing page advertises medication, evaluation, supplies, shipping and nurse access
- Both semaglutide and tirzepatide are listed
- Checked semaglutide campaign states $147 initially, then $297 monthly
What to consider
- Compounded preparations are not FDA-approved products or assumed equivalent across routes
- No-subscription FAQ wording conflicts with the agreement's 30-day recurring charges
- Renewal cancellation requires 48-hour notice; initial-order cancellation has a separate conditional 24-hour window
- Assigned prescribing practice, dispensing pharmacy and selected longer-plan total need confirmation
- Checked campaign excludes Mississippi and Louisiana; confirm state eligibility
Featured provider
Direct Meds
Direct Meds scores 77.6/100 (C+). Direct Meds prices compounded injections and sublingual bottles separately; compare the renewal charge and early cancellation cutoff before choosing a plan.
Commercial relationships affect this placement. The score comparison above is separate.
FDAWarning letter issued to directmeds.com, Inc. dba DirectMeds in September 2025. See the FDA warning-letter database.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.