Head-to-head · WeighScore
Avono Health vs Cost Plus Drugs
The verdict
Too close to call — both grade 58.5/100 (C).
Avono Health and Cost Plus Drugs land on the same WeighScore, so neither clears the other on our six graded dimensions. Avono Health sits one line higher on the board (#369 vs #371) on the underlying tiebreak, but it's a genuine coin-flip — pick on the factors and prices that matter most to you below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Avono Health | Cost Plus Drugs |
|---|---|---|
| WeighScore | 58.5/100 | 58.5/100 |
| Grade | C | C |
| Scorecard rank | #369 | #371 |
| Semaglutide | $269/mo (compounded) | $279/mo (brand Ozempic) |
| Tirzepatide | $349/mo (compounded) | Not disclosed |
| Coverage | Coverage not published | All 50 states |
| Brand-name access | Compounded only | Yes |
| Oral / sublingual | Yes | Injection only |
Graded #369 · C
Strengths
- Transparent tiered pricing from $179/mo (microdose semaglutide injection)
- Full compounded range — semaglutide and tirzepatide, injection and oral, microdose and standard
- Free and discreet shipping; 24/7/365 messaging support; 100% online
- US-licensed clinicians and pharmacies; bundle discounts at 3/6/12 months
Where it loses points
- Medications are compounded, not FDA-approved brand-name
- Compounding pharmacy not publicly named
- State availability not published
- Newer brand with limited independent review history
Graded #371 · C
Strengths
- Transparent pricing: wholesale cost + 15% markup + $5 pharmacy fee, the same for everyone
- Around $279/mo for branded Ozempic — well below typical retail list prices
- Mark Cuban's PBM-disrupting pharmacy, praised by Forbes Health, Wired, and KFF Health News
- Ships to all 50 states; genuine FDA-approved Novo Nordisk Ozempic, not compounded
- Partnered with 9amHealth so you can get prescribed and fill at Cost Plus pricing
Where it loses points
- Fulfillment only — no telehealth intake; you need a prescription from an outside clinician
- Ozempic is FDA-indicated for type 2 diabetes, not weight management — weight-loss use is off-label
- Wegovy availability has been spotty — check current stock before assuming it ships
- No compounded semaglutide or tirzepatide — brand only
- No clinical follow-up — side-effect monitoring falls to your prescribing clinician
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.