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Head-to-head · WeighScore

Avono Health vs CLYR Health

Avono Health
Graded #361

Lower grade

vs+3.5
CLYR Health
Graded #275

Higher grade

The verdict

CLYR Health takes it — 62.2/100 to 58.7/100.

CLYR Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. CLYR Health is a Florida-based telehealth pharmacy offering compounded GLP-1 weight-loss injections alongside sexual-health, longevity and wellness treatments.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueCLYR Health +9
30
39
Dose & formulationCLYR Health +13
75
88
Clinical oversightAvono Health +6
80
74
Labs & monitoringAvono Health +1
53
52
FulfillmentCLYR Health +6
71
77
Contract termsAvono Health +10
47
37
Avono Health · left barCLYR Health · right bar

The numbers

MetricAvono HealthCLYR Health
WeighScore58.7/10062.2/100
GradeCC
Scorecard rank#361#275
Semaglutide$269/mo (compounded)$229/mo (compounded)
Tirzepatide$349/mo (compounded)$249/mo (compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyYes
Oral / sublingualYesYes
Avono Health

Graded #361 · C

Strengths

  • Transparent tiered pricing from $179/mo (microdose semaglutide injection)
  • Full compounded range — semaglutide and tirzepatide, injection and oral, microdose and standard
  • Free and discreet shipping; 24/7/365 messaging support; 100% online
  • US-licensed clinicians and pharmacies; bundle discounts at 3/6/12 months

Where it loses points

  • Medications are compounded, not FDA-approved brand-name
  • Compounding pharmacy not publicly named
  • State availability not published
  • Newer brand with limited independent review history
CLYR Health

Graded #275 · C

Strengths

  • Flat 'any dose, one price' billing so the monthly cost does not rise as your dose climbs
  • LegitScript Certified with a named 503A pharmacy partner (The Pharmacy Hub, Miami FL) and MD Integrations clinicians
  • 3-month prepay drops semaglutide to $189/mo and tirzepatide to $199/mo

Where it loses points

  • State availability gated behind intake; not published on the marketing site
  • Standing monthly rates ($229-249) run above the cheapest compounded competitors
  • Broad catalog (weight loss, sexual health, longevity) rather than a weight-loss specialist

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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