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Head-to-head · WeighScore

Ascend Vitality vs Roen Rx

Ascend Vitality
Graded #307

Higher grade

vs+1.8999999999999986
Roen Rx
Graded #350

Lower grade

The verdict

Ascend Vitality takes it — 60.9/100 to 59/100, but only just.

Ascend Vitality grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Ascend Vitality is a cash-pay GLP-1 telehealth provider offering compounded semaglutide (starting at $199/mo) and compounded tirzepatide (starting at $299/mo) as both weekly injectables and needle-free… Roen Rx is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueAscend Vitality +12
50
38
Dose & formulationRoen Rx +2
75
77
Clinical oversightEven
74
74
Labs & monitoringRoen Rx +1
52
53
FulfillmentRoen Rx +2
65
67
Contract termsRoen Rx +4
37
41
Ascend Vitality · left barRoen Rx · right bar

The numbers

MetricAscend VitalityRoen Rx
WeighScore60.9/10059/100
GradeCC
Scorecard rank#307#350
Semaglutide$199/mo (compounded)$151/mo (3-month plan, plus a separate fee, compounded)
Tirzepatide$299/mo (compounded)$216/mo (plus a separate fee, compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyYes
Oral / sublingualYesInjection only
Ascend Vitality

Graded #307 · C

Strengths

  • Both injectable and needle-free oral tablet forms of semaglutide and tirzepatide
  • LegitScript certified
  • Transparent cash-pay pricing with cancel-anytime subscription
  • Legal entity and address publicly disclosed (Ascend Vitality LLC, Sheridan, WY)

Where it loses points

  • All medications are compounded — FDA does not review compounded drugs for safety/effectiveness
  • No named compounding pharmacy partner disclosed
  • No public state-by-state availability list (homepage cites exclusions: LA, MS, KS, NM, WV)
  • Per-dose/titration pricing not published; only 'starting at' prices shown
Roen Rx

Graded #350 · C

Strengths

  • Insurance coordination for brand-name GLP-1s — as low as $25/mo
  • Both compounded and brand-name options
  • LegitScript approved with Compounded USA badge
  • Compounded semaglutide from $151/mo quarterly
  • Also offers primary care, mental health, and other specialties

Where it loses points

  • State availability not publicly disclosed
  • Insurance coordination may not work for all plans
  • Broader platform (ED, hair loss, skincare, birth control)
  • Requires a separate membership (first month $39); GLP-1 medications are NOT included in the membership fee - medication is billed on top

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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