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Head-to-head · WeighScore

Ascend Vitality vs Enhance MD

Ascend Vitality
Graded #307

Lower grade

vs+23.9
Enhance MD
Graded #11

Higher grade

The verdict

Enhance MD takes it — 84.8/100 to 60.9/100.

Enhance MD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. A transparently tiered compounded program — semaglutide $212/mo (first month $112), tirzepatide $280, a $169 microdose, and a $322 combo — backed by six-month lab testing and provider care, with NAD+ on the side.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueEnhance MD +32
50
82
Dose & formulationEnhance MD +7
75
82
Clinical oversightEnhance MD +14
74
88
Labs & monitoringEnhance MD +38
52
90
FulfillmentEnhance MD +19
65
84
Contract termsEnhance MD +47
37
84
Ascend Vitality · left barEnhance MD · right bar

The numbers

MetricAscend VitalityEnhance MD
WeighScore60.9/10084.8/100
GradeCB
Scorecard rank#307#11
Semaglutide$199/mo (compounded)$212/mo
Tirzepatide$299/mo (compounded)$280/mo
CoverageCoverage not publishedNot publicly listed
Brand-name accessCompounded onlyCompounded only
Oral / sublingualYesInjection only
Ascend Vitality

Graded #307 · C

Strengths

  • Both injectable and needle-free oral tablet forms of semaglutide and tirzepatide
  • LegitScript certified
  • Transparent cash-pay pricing with cancel-anytime subscription
  • Legal entity and address publicly disclosed (Ascend Vitality LLC, Sheridan, WY)

Where it loses points

  • All medications are compounded — FDA does not review compounded drugs for safety/effectiveness
  • No named compounding pharmacy partner disclosed
  • No public state-by-state availability list (homepage cites exclusions: LA, MS, KS, NM, WV)
  • Per-dose/titration pricing not published; only 'starting at' prices shown
Enhance MD

Graded #11 · B

Strengths

  • Transparent tiered pricing across sema, tirz, microdose, and combo
  • Dose-flat — the price does not step up as you titrate
  • Six-month lab testing plus provider-led care
  • NAD+ longevity adjacency available

Where it loses points

  • Compounded only — no brand-name Ozempic/Wegovy or Mounjaro/Zepbound
  • No oral or sublingual route
  • States served are not published
  • Higher entry price than the cheapest compounded programs

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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