Head-to-head · WeighScore
Ascend Vitality vs CLYR Health
The verdict
CLYR Health takes it — 62.2/100 to 60.9/100, but only just.
CLYR Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. CLYR Health is a Florida-based telehealth pharmacy offering compounded GLP-1 weight-loss injections alongside sexual-health, longevity and wellness treatments. Ascend Vitality is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Ascend Vitality | CLYR Health |
|---|---|---|
| WeighScore | 60.9/100 | 62.2/100 |
| Grade | C | C |
| Scorecard rank | #307 | #275 |
| Semaglutide | $199/mo (compounded) | $229/mo (compounded) |
| Tirzepatide | $299/mo (compounded) | $249/mo (compounded) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Yes |
| Oral / sublingual | Yes | Yes |
Graded #307 · C
Strengths
- Both injectable and needle-free oral tablet forms of semaglutide and tirzepatide
- LegitScript certified
- Transparent cash-pay pricing with cancel-anytime subscription
- Legal entity and address publicly disclosed (Ascend Vitality LLC, Sheridan, WY)
Where it loses points
- All medications are compounded — FDA does not review compounded drugs for safety/effectiveness
- No named compounding pharmacy partner disclosed
- No public state-by-state availability list (homepage cites exclusions: LA, MS, KS, NM, WV)
- Per-dose/titration pricing not published; only 'starting at' prices shown
Graded #275 · C
Strengths
- Flat 'any dose, one price' billing so the monthly cost does not rise as your dose climbs
- LegitScript Certified with a named 503A pharmacy partner (The Pharmacy Hub, Miami FL) and MD Integrations clinicians
- 3-month prepay drops semaglutide to $189/mo and tirzepatide to $199/mo
Where it loses points
- State availability gated behind intake; not published on the marketing site
- Standing monthly rates ($229-249) run above the cheapest compounded competitors
- Broad catalog (weight loss, sexual health, longevity) rather than a weight-loss specialist
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.