Head-to-head · WeighScore
Apex MD vs Signos
The verdict
Apex MD takes it — 71.8/100 to 61.4/100.
Apex MD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Apex MD is a US virtual telemedicine platform licensed in all 50 states that prescribes compounded GLP-1 medications for weight loss.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Apex MD | Signos |
|---|---|---|
| WeighScore | 71.8/100 | 61.4/100 |
| Grade | C | C |
| Scorecard rank | #86 | #294 |
| Semaglutide | $299/mo | $199/mo (6-month plan, compounded) |
| Tirzepatide | $399/mo | $199/mo (starting dose, compounded) |
| Coverage | All 50 states | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Injection only |
Graded #86 · C
Strengths
- Licensed in all 50 states
- Unlimited provider visits and Labcorp labs included in the plan
- Both semaglutide and tirzepatide, injectable or oral
- Medication delivery typically in under four business days
Where it loses points
- Compounds bundle NAD, B-12 and L-Carnitine rather than a single-ingredient GLP-1
- Does not publicly name its compounding pharmacy or list an accreditation seal
Graded #294 · C
Strengths
- Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
- Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
- Free rapid shipping; HSA/FSA eligible
- Real-time glucose insights and app coaching to help sustain results after GLP-1
Where it loses points
- Compounded GLP-1s are not FDA-approved finished products
- Headline price is a 6-month-program rate, not month-to-month
- Only semaglutide is shown in the program; tirzepatide availability is not confirmed
- Compounding pharmacy partner and state availability are not published on the landing page
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.