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Head-to-head · WeighScore

Ambiante Health & Wellness vs Signos

Ambiante Health & Wellness
Graded #448

Lower grade

vs+6.399999999999999
Signos
Graded #293

Higher grade

The verdict

Signos takes it — 61.4/100 to 55/100.

Signos grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Signos (Signos+) is a metabolic-health platform that bundles clinician-prescribed compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor (CGM) and app — pairing the medication with…

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Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueAmbiante Health & Wellness +1
45
44
Dose & formulationSignos +24
40
64
Clinical oversightSignos +6
78
84
Labs & monitoringSignos +18
53
71
FulfillmentSignos +6
65
71
Contract termsAmbiante Health & Wellness +35
55
20
Ambiante Health & Wellness · left barSignos · right bar

The numbers

MetricAmbiante Health & WellnessSignos
WeighScore55/10061.4/100
GradeCC
Scorecard rank#448#293
SemaglutideNot disclosed$199/mo (6-month plan, compounded)
TirzepatideNot disclosed$199/mo (starting dose, compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only

Strengths

  • Compounded semaglutide and tirzepatide plus a low-dose GLP-1 "Longevity Microdose" option, all provider-guided
  • Concierge model: dedicated provider, direct secure messaging, provider-directed dosing, and structured check-ins
  • Every plan bundles compounded medication, provider care, and discreet direct delivery with no hidden fees
  • No charge if you are not approved; published support hours (Mon-Fri, 9am-5pm ET) by phone and email

Where it loses points

  • GLP-1 program pricing is not published on the site — quoted only after provider review, so cost is not comparable up front
  • Compounding pharmacy partners are not publicly named (a transparency gap for medication sourcing)
  • No brand-name Wegovy, Zepbound, Mounjaro, or Ozempic — compounded formulations only
  • State availability is not published; private-pay only, and the practice serves women, so it is not a fit for everyone
  • No LegitScript or PCAB accreditation displayed on the marketing site
Signos

Graded #293 · C

Strengths

  • Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
  • Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
  • Free rapid shipping; HSA/FSA eligible
  • Real-time glucose insights and app coaching to help sustain results after GLP-1

Where it loses points

  • Compounded GLP-1s are not FDA-approved finished products
  • Headline price is a 6-month-program rate, not month-to-month
  • Only semaglutide is shown in the program; tirzepatide availability is not confirmed
  • Compounding pharmacy partner and state availability are not published on the landing page

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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