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Head-to-head · WeighScore

AlyveRx vs Sesame Care

AlyveRx
Site position #116

Lower grade

vs+17.3
Sesame Care
Site position #2

Higher grade

The verdict

Sesame Care takes it — 87.8/100 to 70.5/100.

Sesame Care grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. An established national telehealth marketplace with the widest real brand-name GLP-1 access in the ranking — Wegovy (pen and pill), Zepbound, Ozempic and Mounjaro — plus provider-by-provider price transparency.

We may earn a commission through these links, at no extra cost to you. Commercial relationships affect placement, but never the WeighScore or our editorial findings. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueSesame Care +15
69
84
Dose & formulationAlyveRx +4
96
92
Clinical oversightSesame Care +23
71
94
Labs & monitoringSesame Care +32
52
84
FulfillmentSesame Care +16
64
80
Contract termsSesame Care +37
55
92
AlyveRx · left barSesame Care · right bar

The numbers

MetricAlyveRxSesame Care
WeighScore70.5/10087.8/100
GradeCB+
Site position#116#2
Semaglutide$183/mo (all doses, compounded)Brand Wegovy pill from $149/mo at 1.5 and 4 mg only, $299/mo at 9 and 25 mg — plus Sesame care: $59/mo only on the 12-month prepay, otherwise $99 billed every 28 days (13 charges a year)
Tirzepatide$249/mo (all doses, compounded)Brand Zepbound vial $299/mo (2.5 mg), $399 (5 mg), $449 (7.5–15 mg); KwikPen $299 / $399 / $499 / $699 (10–15 mg) — plus Sesame care: $59/mo on the 12-month prepay, otherwise $99 per 28 days
CoverageCoverage not publishedNationwide marketplace
Brand-name accessYesYes
Oral / sublingualYesYes
AlyveRx

Site position #116 · C

Strengths

  • Offers compounded semaglutide and tirzepatide as both injections and needle-free sublingual drops for people who dislike needles
  • Transparent monthly pricing shown upfront, no insurance required, and free discreet delivery
  • Also carries brand-name Ozempic, Wegovy, and Mounjaro through its provider network

Where it loses points

  • Does not publicly name its dispensing pharmacy or display a LegitScript seal, so third-party accreditation is unverified
  • Sublingual GLP-1 absorption relies on the company proprietary PermeAct technology and is not FDA-reviewed for weight loss
  • State availability is not published on the site
Sesame Care

Site position #2 · B+

Strengths

  • Real FDA-approved brand-name access — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and Rybelsus
  • Established platform (operating since 2018) with LegitScript, BBB accreditation and large third-party review volume
  • You choose the provider and see the price up front — genuine marketplace transparency
  • Oral routes available (Wegovy pill, Rybelsus)

Where it loses points

  • A generalist marketplace, not a dedicated weight-loss program — lighter ongoing hand-holding than a specialist desk
  • Two-part cost (a platform subscription plus the medication) makes the true monthly total harder to compare
  • Brand-name cash prices can run high without insurance

Featured provider

Sesame Care

Sesame Care scores 87.8/100 (B+). An established national telehealth marketplace with the widest real brand-name GLP-1 access in the ranking — Wegovy (pen and pill), Zepbound, Ozempic and Mounjaro — plus provider-by-provider price transparency.

Commercial relationships affect this placement. The score comparison above is separate.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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