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Head-to-head · WeighScore

Alegro Health vs Signos

Alegro Health
Graded #352

Lower grade

vs+2.5
Signos
Graded #293

Higher grade

The verdict

Signos takes it — 61.4/100 to 58.9/100.

Signos grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Signos (Signos+) is a metabolic-health platform that bundles clinician-prescribed compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor (CGM) and app — pairing the medication with…

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Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueAlegro Health +10
54
44
Dose & formulationSignos +12
52
64
Clinical oversightSignos +14
70
84
Labs & monitoringSignos +9
62
71
FulfillmentSignos +14
57
71
Contract termsAlegro Health +41
61
20
Alegro Health · left barSignos · right bar

The numbers

MetricAlegro HealthSignos
WeighScore58.9/10061.4/100
GradeCC
Scorecard rank#352#293
Semaglutide$199/mo (starting dose, compounded)$199/mo (6-month plan, compounded)
TirzepatideNot disclosed$199/mo (starting dose, compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
Alegro Health

Graded #352 · C

Strengths

  • Low-cost entry point: 199 dollars for a full 8-week semaglutide starter with B12
  • Direct shipping with no recurring monthly fees
  • Operates from a physical Texas medical practice with a published phone number

Where it loses points

  • Semaglutide only; no tirzepatide offered
  • Available in select states only, which are not enumerated
  • Thin public information and compounding pharmacy not named on the site
Signos

Graded #293 · C

Strengths

  • Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
  • Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
  • Free rapid shipping; HSA/FSA eligible
  • Real-time glucose insights and app coaching to help sustain results after GLP-1

Where it loses points

  • Compounded GLP-1s are not FDA-approved finished products
  • Headline price is a 6-month-program rate, not month-to-month
  • Only semaglutide is shown in the program; tirzepatide availability is not confirmed
  • Compounding pharmacy partner and state availability are not published on the landing page

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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