Head-to-head · WeighScore
1st Optimal vs TRYM Health
The verdict
TRYM Health takes it — 73.6/100 to 61.6/100.
TRYM Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. TRYM Health (TRYM) is a nationwide telehealth service offering compounded GLP-1 weight-loss medication — semaglutide (~$96/mo, $3.20/day) and tirzepatide (~$126/mo, $4.20/day) — as additive-free multi-dose…
We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | 1st Optimal | TRYM Health |
|---|---|---|
| WeighScore | 61.6/100 | 73.6/100 |
| Grade | C | C |
| Scorecard rank | #291 | #71 |
| Semaglutide | Not disclosed | $96/mo (all doses, compounded) |
| Tirzepatide | Not disclosed | $126/mo (all doses, compounded) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Injection only |
Graded #291 · C
Strengths
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Where it loses points
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
Graded #71 · C
Strengths
- Affordable compounded GLP-1 — semaglutide ~$96/mo ($3.20/day) and tirzepatide ~$126/mo ($4.20/day)
- Available in all 50 states with free shipping and FSA/HSA eligibility
- Multi-dose vials cover all doses up to the maximum; additive-free, with a full starter kit
- Temperature-controlled insulated shipping and flexible cancellation
Where it loses points
- Compounding pharmacy partner not named
- Not LegitScript-certified (no certification displayed)
- Lowest per-day pricing likely requires a longer prepaid plan commitment
- Drugs labeled generically as 'GLP-1' / 'GLP-1 + GIP' on the services page rather than named
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.