Head-to-head · WeighScore
1st Optimal vs TRT Nation
The verdict
TRT Nation takes it — 63.1/100 to 61.6/100, but only just.
TRT Nation grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. TRT Nation is a men's telehealth platform focused primarily on testosterone replacement therapy, with compounded GLP-1 weight loss as a secondary vertical. 1st Optimal is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | 1st Optimal | TRT Nation |
|---|---|---|
| WeighScore | 61.6/100 | 63.1/100 |
| Grade | C | C |
| Scorecard rank | #288 | #260 |
| Semaglutide | Not disclosed | Not disclosed |
| Tirzepatide | Not disclosed | $219/mo |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Injection only |
Graded #288 · C
Strengths
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Where it loses points
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
Graded #260 · C
Strengths
- Flat $219/mo tirzepatide regardless of dose escalation
- Tirzepatide compounded with B12 to reduce nausea
- Flat plan includes unlimited virtual provider visits
- Fully online intake-to-delivery process
- Compounded from licensed US pharmacies
Where it loses points
- Weight loss is secondary to core TRT business
- Specific pharmacy partner and 503A status not disclosed
- Compounded only; not FDA-approved formulations
- State licensing list not published
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.