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Head-to-head · WeighScore

1st Optimal vs Trinity Meds

1st Optimal
Graded #291

Higher grade

vs+0.3999999999999986
Trinity Meds
Graded #302

Lower grade

The verdict

1st Optimal takes it — 61.6/100 to 61.2/100, but only just.

1st Optimal grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. 1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Trinity Meds is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueTrinity Meds +19
45
64
Dose & formulationTrinity Meds +13
51
64
Clinical oversight1st Optimal +3
77
74
Labs & monitoring1st Optimal +45
97
52
FulfillmentTrinity Meds +8
60
68
Contract terms1st Optimal +17
37
20
1st Optimal · left barTrinity Meds · right bar

The numbers

Metric1st OptimalTrinity Meds
WeighScore61.6/10061.2/100
GradeCC
Scorecard rank#291#302
SemaglutideNot disclosed$149/mo (compounded)
TirzepatideNot disclosed$199/mo (compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualYesInjection only
1st Optimal

Graded #291 · C

Strengths

  • Offers both semaglutide and tirzepatide with injectable and oral formats
  • Functional-medicine approach with at-home labs and blood-work interpretation
  • Unlimited coaching and ongoing support included
  • No long-term contracts
  • Board-certified doctors and nurse practitioners referenced

Where it loses points

  • No public monthly pricing disclosed
  • No published state availability list
  • Compounded vs branded sourcing not clarified on site
  • Pricing only revealed after quiz or consultation
Trinity Meds

Graded #302 · C

Strengths

  • All-inclusive flat pricing — $149/month semaglutide, same price at every dose, no hidden fees
  • Multi-month plans cut the cost further (semaglutide to $129/month, tirzepatide to $149/month)
  • No insurance required, FSA eligible, with free shipping to your door
  • Named operating entity (Trinity Meds Inc) and US-licensed clinicians via CareValidate Health

Where it loses points

  • Doesn't publish the states it serves — you only learn eligibility after starting the assessment
  • Pharmacy partners are described as 'multiple USA certified pharmacies' but none are named
  • No terms-of-service page is posted (only a privacy policy)
  • Compounded semaglutide and tirzepatide only — no brand-name or oral options
  • Military framing is marketing; the program and pricing are open to anyone who qualifies

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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