Head-to-head · WeighScore
1st Optimal vs RxSpan MD
The verdict
RxSpan MD takes it — 86.8/100 to 61.6/100.
RxSpan MD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. A physician-led telehealth under board-certified founder Dr. John Diaz with a broad GLP-1 menu — compounded semaglutide and tirzepatide by injection or oral capsule, plus a brand-name lane and microdosing — on transparent all-inclusive pricing to all 50 states.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | 1st Optimal | RxSpan MD |
|---|---|---|
| WeighScore | 61.6/100 | 86.8/100 |
| Grade | C | B |
| Scorecard rank | #291 | #4 |
| Semaglutide | Not disclosed | From $194/mo |
| Tirzepatide | Not disclosed | $329/mo |
| Coverage | Coverage not published | All 50 states |
| Brand-name access | Compounded only | Yes |
| Oral / sublingual | Yes | Yes |
Graded #291 · C
Strengths
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Where it loses points
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
Graded #4 · B
Strengths
- Available in all 50 states
- Transparent, all-inclusive published pricing — consult, medication, supplies, shipping and support, cancel anytime, from ~$194/mo compounded semaglutide on an annual plan
- Both injectable and a real oral (capsule) route, plus compounded and an advertised brand-name lane
- Physician-led by a named, board-certified founder (Dr. John Diaz) with 24/7 messaging and coaching
Where it loses points
- Compounded semaglutide/tirzepatide are not FDA-approved (not the same as Wegovy/Ozempic/Zepbound)
- Published pricing is for the compounded line — brand-name pricing isn’t itemized
- A prescription isn’t guaranteed — a provider reviews eligibility after checkout
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.