Head-to-head · WeighScore
1st Optimal vs Rex MD
The verdict
Rex MD takes it — 70.2/100 to 61.6/100.
Rex MD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Rex MD is a US-based men's-health telehealth platform (a LifeMD brand) offering a 100 percent online GLP-1 weight-management program.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | 1st Optimal | Rex MD |
|---|---|---|
| WeighScore | 61.6/100 | 70.2/100 |
| Grade | C | C |
| Scorecard rank | #291 | #112 |
| Semaglutide | Not disclosed | $199/mo (brand-name) |
| Tirzepatide | Not disclosed | $349/mo (brand Zepbound) |
| Coverage | Coverage not published | All 50 states |
| Brand-name access | Compounded only | Yes |
| Oral / sublingual | Yes | Injection only |
Graded #291 · C
Strengths
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Where it loses points
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
Graded #112 · C
Strengths
- Flat $199/mo program bundles consult, medication and overnight shipping
- Brand-name semaglutide and Zepbound vials, not just compounded
- Serves all 50 states, fully online
- LegitScript certified with US-based, state-licensed providers
- Backed by parent company LifeMD
Where it loses points
- Does not accept insurance
- Marketed primarily to men via a men's-health platform
- Zepbound vial cost rises with dose titration
- Branded-only program costs more than compounded options
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.