Head-to-head · WeighScore
1st Optimal vs Mixx Health & Wellness
The verdict
Mixx Health & Wellness takes it — 62.8/100 to 61.6/100, but only just.
Mixx Health & Wellness grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Mixx Health & Wellness is a telehealth weight-loss platform offering compounded semaglutide and tirzepatide from $120/month with $0 consultations and follow-ups. 1st Optimal is close behind and may still be the better fit — see the factor split below.
We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | 1st Optimal | Mixx Health & Wellness |
|---|---|---|
| WeighScore | 61.6/100 | 62.8/100 |
| Grade | C | C |
| Scorecard rank | #288 | #266 |
| Semaglutide | Not disclosed | Not disclosed |
| Tirzepatide | Not disclosed | Not disclosed |
| Coverage | Coverage not published | 44 states |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Injection only |
Graded #288 · C
Strengths
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Where it loses points
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
Graded #266 · C
Strengths
- 44 jurisdictions enumerated in the public FAQ — confirm eligibility before intake
- Operating LLC disclosed: Mixx Health and Wellness LLC (Wyoming law)
- Named pharmacy partner: Promise Pharmacy, Palm Harbor FL, (727) 772-0500
- Named founder: Dr. James David Lawrence III, MD, with a public origin story
- $0 consultation fee — free intake and follow-ups
Where it loses points
- Both medications are compounded semaglutide and tirzepatide — not FDA-approved brand drugs
- Dose-tier pricing not available — /pricing and /products pages returned 404
- No LegitScript, PCAB, or BBB trust badges visible
- Wyoming governing-law clause — disputes adjudicated under Wyoming law regardless of your state
- FDA has issued this company a warning letter; the letter is public in FDA's warning-letter database
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.